G protein‐coupled receptors (GPCRs) are the largest family of membrane receptors and
major targets for FDA‐approved drugs. The ability to quantify GPCR expression and ligand …

The MYC oncogene has been studied for decades, yet there is still intense debate over how
this transcription factor controls gene expression. Here, we seek to answer these questions …

G protein-coupled receptors are a major class of membrane receptors that mediate
physiological and pathophysiological cellular signaling. Many aspects of receptor activation …

Simple Summary We comparatively discuss all possible methodologies for the complex
DNA damage in situ detection. Fluorescent microscopy (FM) is the universal approach …

To study the localisation of G protein-coupled receptors (GPCR) in their native cellular
environment requires their visualisation through fluorescent labelling. To overcome the …

During organismal development, homeostasis, and disease, Dishevelled (Dvl) proteins act
as key signaling factors in beta-catenin–dependent and beta-catenin–independent Wnt …

Cells migrating through complex 3D environments experience considerable physical
challenges including tensile stress and compression. To move, cells need to resist these …

In specialized cells, the expression of specific tubulin isoforms and their subsequent post-
translational modifications drive and coordinate unique morphologies and behaviors. The …

Cells migrating through complex three-dimensional environments experience considerable
physical challenges, including tensile stress and compression. To move, cells need to resist …

Single-molecule localization microscopy (SMLM) reports on protein organization in cells
with near-molecular resolution and in combination with stoichiometric labeling enables …