A microfluidic Braille valve platform for on-demand production, combinatorial screening and sorting of chemically distinct droplets
R Utharala, A Grab, V Vafaizadeh, N Peschke… - Nature protocols, 2022 - nature.com
Droplet microfluidics is a powerful tool for a variety of biological applications including single-
cell genetics, antibody discovery and directed evolution. All these applications make use of …
cell genetics, antibody discovery and directed evolution. All these applications make use of …
Recent advances in droplet-based microfluidic technologies for biochemistry and molecular biology
Recently, droplet-based microfluidic systems have been widely used in various biochemical
and molecular biological assays. Since this platform technique allows manipulation of large …
and molecular biological assays. Since this platform technique allows manipulation of large …
A microfluidics platform for combinatorial drug screening on cancer biopsies
Screening drugs on patient biopsies from solid tumours has immense potential, but is
challenging due to the small amount of available material. To address this, we present here …
challenging due to the small amount of available material. To address this, we present here …
NF-κB inhibitor with Temozolomide results in significant apoptosis in glioblastoma via the NF-κB (p65) and actin cytoskeleton regulatory pathways
Glioblastoma (GBM) is the most malignant brain tumor characterized by intrinsic or acquired
resistance to chemotherapy. GBM tumors show nuclear factor-κB (NF-κB) activity that has …
resistance to chemotherapy. GBM tumors show nuclear factor-κB (NF-κB) activity that has …
[HTML][HTML] Selectable encapsulated cell quantity in droplets via label-free electrical screening and impedance-activated sorting
Single-cell encapsulation in droplets has become a powerful tool in immunotherapy,
medicine discovery, and single-cell analysis, thanks to its capability for cell confinement in …
medicine discovery, and single-cell analysis, thanks to its capability for cell confinement in …
Microfluidics as an enabling technology for personalized cancer therapy
Tailoring patient‐specific treatments for cancer is necessary in order to achieve optimal
results but requires new diagnostic approaches at affordable prices. Microfluidics has …
results but requires new diagnostic approaches at affordable prices. Microfluidics has …
Recent progress in CRISPR-based microfluidic assays and applications
P Li, H **ong, B Yang, X Jiang, J Kong… - TrAC Trends in Analytical …, 2022 - Elsevier
In the past few years, CRISPR-based (Clustered regularly interspaced short palindromic
repeats-based) detection techniques have arisen in the field of bioanalysis, molecular …
repeats-based) detection techniques have arisen in the field of bioanalysis, molecular …
3D cell electrorotation and imaging for measuring multiple cellular biophysical properties
L Huang, P Zhao, W Wang - Lab on a Chip, 2018 - pubs.rsc.org
3D rotation is one of many fundamental manipulations to cells and imperative in a wide
range of applications in single cell analysis involving biology, chemistry, physics and …
range of applications in single cell analysis involving biology, chemistry, physics and …
On-chip anticancer drug screening–Recent progress in microfluidic platforms to address challenges in chemotherapy
There is an increasing need for advanced and inexpensive preclinical models to accelerate
the development of anticancer drugs. While costly animal models fail to predict human …
the development of anticancer drugs. While costly animal models fail to predict human …
Cancer drug screening with an on-chip multi-drug dispenser in digital microfluidics
Microfluidics has been the most promising platform for drug screening with a limited number
of cells. However, convenient on-chip preparation of a wide range of drug concentrations …
of cells. However, convenient on-chip preparation of a wide range of drug concentrations …