Bringing machine learning to research on intellectual and developmental disabilities: taking inspiration from neurological diseases

C Gupta, P Chandrashekar, T **, C He… - Journal of …, 2022 - Springer
Abstract Intellectual and Developmental Disabilities (IDDs), such as Down syndrome,
Fragile X syndrome, Rett syndrome, and autism spectrum disorder, usually manifest at birth …

[HTML][HTML] Gut microbiota-brain bile acid axis orchestrates aging-related neuroinflammation and behavior impairment in mice

J Ma, M Li, Y Bao, W Huang, X He, Y Hong… - Pharmacological …, 2024 - Elsevier
Emerging evidence shows that disrupted gut microbiota-bile acid (BA) axis is critically
involved in the development of neurodegenerative diseases. However, the alterations in …

[HTML][HTML] Bridging between mouse and human enhancer-promoter long-range interactions in neural stem cells, to understand enhancer function in …

R D'Aurizio, O Catona, M Pitasi, YE Li, B Ren… - International journal of …, 2022 - mdpi.com
Non-coding variation in complex human disease has been well established by genome-
wide association studies, and is thought to involve regulatory elements, such as enhancers …