[PDF][PDF] Hyaluronic acid in inflammation and tissue regeneration

M Litwiniuk, A Krejner, MS Speyrer, AR Gauto… - Wounds, 2016‏ - magistralbr.caldic.com
Hyaluronic acid (HA), the main component of extracellular matrix, is considered one of the
key players in the tissue regeneration process. It has been proven to modulate via specific …

Scavenger receptors in host defense: from functional aspects to mode of action

Q Taban, PT Mumtaz, KZ Masoodi, E Haq… - Cell Communication and …, 2022‏ - Springer
Scavenger receptors belong to a superfamily of proteins that are structurally heterogeneous
and encompass the miscellaneous group of transmembrane proteins and soluble secretory …

Co-operation of TLR4 and raft proteins in LPS-induced pro-inflammatory signaling

A Płóciennikowska, A Hromada-Judycka… - Cellular and molecular …, 2015‏ - Springer
Abstract Toll-like receptor 4 (TLR4) is activated by lipopolysaccharide (LPS), a component of
Gram-negative bacteria to induce production of pro-inflammatory mediators aiming at …

Hyaluronan as an immune regulator in human diseases

D Jiang, J Liang, PW Noble - Physiological reviews, 2011‏ - journals.physiology.org
Accumulation and turnover of extracellular matrix components are the hallmarks of tissue
injury. Fragmented hyaluronan stimulates the expression of inflammatory genes by a variety …

Anti-inflammatory protein TSG-6 secreted by activated MSCs attenuates zymosan-induced mouse peritonitis by decreasing TLR2/NF-κB signaling in resident …

H Choi, RH Lee, N Bazhanov, JY Oh… - Blood, The Journal of …, 2011‏ - ashpublications.org
Human mesenchymal stem/progenitor cells (hMSCs) repair tissues and modulate immune
systems but the mechanisms are not fully understood. We demonstrated that hMSCs are …

Hyaluronan: biosynthesis and signaling

D Vigetti, E Karousou, M Viola, S Deleonibus… - … et Biophysica Acta (BBA …, 2014‏ - Elsevier
Background Hyaluronan is a critical component of extracellular matrix with several different
roles. Besides the contribution to the tissue hydration, mechanical properties and correct …

Hyaluronan in wound healing: rediscovering a major player

KL Aya, R Stern - Wound repair and regeneration, 2014‏ - Wiley Online Library
Wound healing involves a series of carefully modulated steps, from initial injury and blood
clot to the final reconstituted tissue or scar. A dynamic reciprocity exists throughout between …

Hyaluronan as a therapeutic target in human diseases

J Liang, D Jiang, PW Noble - Advanced Drug Delivery Reviews, 2016‏ - Elsevier
Accumulation and turnover of extracellular matrix is a hallmark of tissue injury, repair and
remodeling in human diseases. Hyaluronan is a major component of the extracellular matrix …

Extracellular matrix regulation of inflammation in the healthy and injured spinal cord

AD Gaudet, PG Popovich - Experimental neurology, 2014‏ - Elsevier
Throughout the body, the extracellular matrix (ECM) provides structure and organization to
tissues and also helps regulate cell migration and intercellular communication. In the injured …

Extracellular DAMPs in plants and mammals: immunity, tissue damage and repair

G De Lorenzo, S Ferrari, F Cervone, E Okun - Trends in immunology, 2018‏ - cell.com
Innate immune receptors, well known mediators of response to non-self-molecules and
inflammation, also act as mediators of immunity triggered by 'damage-associated molecular …