IL-6/JAK/STAT3 signaling in breast cancer metastasis: biology and treatment

SG Manore, DL Doheny, GL Wong, HW Lo - Frontiers in oncology, 2022 - frontiersin.org
Breast cancer is the most commonly diagnosed cancer in women. Metastasis is the primary
cause of mortality for breast cancer patients. Multiple mechanisms underlie breast cancer …

Galangin as an inflammatory response modulator: An updated overview and therapeutic potential

R Thapa, O Afzal, ASA Altamimi, A Goyal… - Chemico-biological …, 2023 - Elsevier
Numerous chronic diseases, such as cancer, diabetes, rheumatoid arthritis, cardiovascular
disease, and gastrointestinal disorders, all have an inflammation-based etiology. In cellular …

Honey bee products: preclinical and clinical studies of their anti-inflammatory and immunomodulatory properties

HR El-Seedi, N Eid, AA Abd El-Wahed, ME Rateb… - Frontiers in …, 2022 - frontiersin.org
Inflammation is a defense process triggered when the body faces assaults from pathogens,
toxic substances, microbial infections, or when tissue is damaged. Immune and inflammatory …

[HTML][HTML] An updated review of functional ingredients of Manuka honey and their value-added innovations

S Wang, Y Qiu, F Zhu - Food chemistry, 2024 - Elsevier
Manuka honey (MH) is a highly prized natural product from the nectar of Leptospermum
scoparium flowers. Increased competition on the global market drives MH product …

Citrus Flavones: An Update on Sources, Biological Functions, and Health Promoting Properties

D Barreca, G Mandalari, A Calderaro, A Smeriglio… - Plants, 2020 - mdpi.com
Citrus spp. are among the most widespread plants cultivated worldwide and every year
millions of tons of fruit, juices, or processed compounds are produced and consumed …

Composition, functional properties and safety of honey: a review

H Wang, L Li, X Lin, W Bai, G **ao… - Journal of the Science of …, 2023 - Wiley Online Library
Honey has been used not only as a food source but also for medicinal purposes. Recent
studies have indicated that honey exhibits antioxidant, hepatoprotective, hypolipidemic …

The immunomodulatory effects of honey and associated flavonoids in cancer

RJ Masad, SM Haneefa, YA Mohamed, A Al-Sbiei… - Nutrients, 2021 - mdpi.com
Honey has exerted a high impact in the field of alternative medicine over many centuries. In
addition to its wound healing, anti-microbial and antioxidant properties, several lines of …

Manuka honey, a unique mono-floral honey. A comprehensive review of its bioactives, metabolism, action mechanisms, and therapeutic merits

FF El-Senduny, NM Hegazi, GE Abd Elghani, MA Farag - Food Bioscience, 2021 - Elsevier
Manuka honey (MH) is a mono-floral honey obtained from the Manuka tree (Leptospermum
scoparium) belonging to the Myrtaceae family and grows as a shrub or a small tree mostly …

Selected flavonols in breast and gynecological cancer: a systematic review

D Wendlocha, K Krzykawski, A Mielczarek-Palacz… - Nutrients, 2023 - mdpi.com
The consumption of foods that are rich in phenolic compounds has chemopreventive effects
on many cancers, including breast cancer, ovarian cancer, and endometrial cancer. A wide …

Differential in vitro cytotoxic effects and metabolomic insights into raw and powdered Manuka honey through UPLC-Q-TOF-MS

I Idriss, AH Ali, A Alam, M Fernandez-Cabezudo… - Scientific reports, 2024 - nature.com
Manuka honey (MH) has garnered much attention due to its remarkable antimicrobial,
anticancer, immunomodulatory and wound-healing properties. This study compared the …