The TRIPOD-LLM reporting guideline for studies using large language models

J Gallifant, M Afshar, S Ameen, Y Aphinyanaphongs… - Nature Medicine, 2025 - nature.com
Large language models (LLMs) are rapidly being adopted in healthcare, necessitating
standardized reporting guidelines. We present transparent reporting of a multivariable …

A future role for health applications of large language models depends on regulators enforcing safety standards

O Freyer, IC Wiest, JN Kather, S Gilbert - The Lancet Digital Health, 2024 - thelancet.com
Among the rapid integration of artificial intelligence in clinical settings, large language
models (LLMs), such as Generative Pre-trained Transformer-4, have emerged as …

Large language model–based responses to patients' in-basket messages

WR Small, B Wiesenfeld, B Brandfield-Harvey… - JAMA network …, 2024 - jamanetwork.com
Importance Virtual patient-physician communications have increased since 2020 and
negatively impacted primary care physician (PCP) well-being. Generative artificial …

A strategy for cost-effective large language model use at health system-scale

E Klang, D Apakama, EE Abbott, A Vaid… - NPJ digital …, 2024 - nature.com
Large language models (LLMs) can optimize clinical workflows; however, the economic and
computational challenges of their utilization at the health system scale are underexplored …

GPT-4 assistance for improvement of physician performance on patient care tasks: a randomized controlled trial

E Goh, RJ Gallo, E Strong, Y Weng, H Kerman… - Nature Medicine, 2025 - nature.com
While large language models (LLMs) have shown promise in diagnostic reasoning, their
impact on management reasoning, which involves balancing treatment decisions and …

Medec: A benchmark for medical error detection and correction in clinical notes

AB Abacha, W Yim, Y Fu, Z Sun, M Yetisgen… - arxiv preprint arxiv …, 2024 - arxiv.org
Several studies showed that Large Language Models (LLMs) can answer medical questions
correctly, even outperforming the average human score in some medical exams. However …

[HTML][HTML] Digital information ecosystems in modern care coordination and patient care pathways and the challenges and opportunities for AI solutions

Y Chen, CU Lehmann, B Malin - Journal of Medical Internet Research, 2024 - jmir.org
The integration of digital technologies into health care has significantly enhanced the
efficiency and effectiveness of care coordination. Our perspective paper explores the digital …

From text to treatment: the crucial role of validation for generative large language models in health care

A de Hond, T Leeuwenberg, R Bartels… - The Lancet Digital …, 2024 - thelancet.com
Generative large language models (LLMs) have made incredible progress and are
speculated to become the next big revolution in health care. Researchers have described …

Retrieval-augmented generation for generative artificial intelligence in medicine

R Yang, Y Ning, E Keppo, M Liu, C Hong… - arxiv preprint arxiv …, 2024 - arxiv.org
Generative artificial intelligence (AI) has brought revolutionary innovations in various fields,
including medicine. However, it also exhibits limitations. In response, retrieval-augmented …

[HTML][HTML] Impact of a digital scribe system on clinical documentation time and quality: usability study

MM van Buchem, IMJ Kant, L King, J Kazmaier… - JMIR AI, 2024 - ai.jmir.org
Background: Physicians spend approximately half of their time on administrative tasks,
which is one of the leading causes of physician burnout and decreased work satisfaction …