Deep learning in ophthalmology: the technical and clinical considerations

DSW Ting, L Peng, AV Varadarajan, PA Keane… - Progress in retinal and …, 2019 - Elsevier
The advent of computer graphic processing units, improvement in mathematical models and
availability of big data has allowed artificial intelligence (AI) using machine learning (ML) …

Ten years of anti-vascular endothelial growth factor therapy

N Ferrara, AP Adamis - Nature reviews Drug discovery, 2016 - nature.com
The targeting of vascular endothelial growth factor A (VEGFA), a crucial regulator of both
normal and pathological angiogenesis, has revealed innovative therapeutic approaches in …

[HTML][HTML] Global prevalence of age-related macular degeneration and disease burden projection for 2020 and 2040: a systematic review and meta-analysis

WL Wong, X Su, X Li, CMG Cheung, R Klein… - The Lancet Global …, 2014 - thelancet.com
Background Numerous population-based studies of age-related macular degeneration have
been reported around the world, with the results of some studies suggesting racial or ethnic …

Age-related macular degeneration preferred practice pattern®

CJ Flaxel, RA Adelman, ST Bailey, A Fawzi, JI Lim… - …, 2020 - aaojournal.org
Background: Age-related macular degeneration is a leading cause of severe, irreversible
vision impairment in developed countries. The primary risk factors for the development of …

Intravitreal aflibercept injection for neovascular age-related macular degeneration: ninety-six–week results of the VIEW studies

U Schmidt-Erfurth, PK Kaiser, JF Korobelnik, DM Brown… - Ophthalmology, 2014 - Elsevier
Purpose To determine efficacy and safety of intravitreal aflibercept in patients with
neovascular age-related macular degeneration (AMD) during a second year of variable …

[HTML][HTML] Updates on the epidemiology of age-related macular degeneration

JB Jonas, CMG Cheung, S Panda-Jonas - Asia-Pacific Journal of …, 2017 - Elsevier
This meta-analysis reports on current estimates of the prevalence of age-related macular
degeneration (AMD) based on a review of recent meta-analyses and literature research …

Mechanisms of age‐related macular degeneration and therapeutic opportunities

M van Lookeren Campagne, J LeCouter… - The Journal of …, 2014 - Wiley Online Library
As the age of the population increases in many nations, age‐related degenerative diseases
pose significant socioeconomic challenges. One of the key degenerative diseases that …

Incidence of legal blindness from age-related macular degeneration in Denmark: year 2000 to 2010

SB Bloch, M Larsen, IC Munch - American journal of ophthalmology, 2012 - Elsevier
PURPOSE: To report incidence rates of legal blindness from age-related macular
degeneration (AMD) and other causes in Denmark from years 2000 to 2010 in the age …

Ultrahigh-speed swept-source OCT angiography in exudative AMD

E Moult, WJ Choi, NK Waheed, M Adhi… - … Surgery, Lasers and …, 2014 - journals.healio.com
BACKGROUND AND OBJECTIVE: To investigate the potential of ultrahigh-speed swept-
source optical coherence tomography angiography (OCTA) to visualize retinal and choroidal …

Anti-vascular endothelial growth factor in neovascular age-related macular degeneration–a systematic review of the impact of anti-VEGF on patient outcomes and …

RP Finger, V Daien, BM Eldem, JS Talks… - BMC …, 2020 - Springer
Background Systematically review the evidence describing the impact of anti–vascular
endothelial growth factor (anti-VEGF) therapy on neovascular age-related macular …