Stem cell based therapies for age-related macular degeneration: the promises and the challenges

H Nazari, L Zhang, D Zhu, GJ Chader… - Progress in retinal and …, 2015 - Elsevier
Age-related macular degeneration (AMD) is the leading cause of blindness among the
elderly in developed countries. AMD is classified as either neovascular (NV-AMD) or non …

Intravitreal dexamethasone implant as a sustained release drug delivery device for the treatment of ocular diseases: a comprehensive review of the literature

C Iovino, R Mastropasqua, M Lupidi, D Bacherini… - Pharmaceutics, 2020 - mdpi.com
Drug delivery into the vitreous chamber remains a great challenge in the pharmaceutical
industry due to the complex anatomy and physiology of the eye. Intravitreal injection is the …

Long-term clinical outcome and causes of vision loss in patients with uveitis

O Tomkins-Netzer, L Talat, A Bar, A Lula, SRJ Taylor… - Ophthalmology, 2014 - Elsevier
Purpose To evaluate the long-term clinical and functional outcome, risks, and causes of
vision loss and burden of disease among patients with uveitis. Design Cross-sectional study …

Multicenter study of intravitreal dexamethasone implant in noninfectious uveitis: indications, outcomes, and reinjection frequency

J Zarranz-Ventura, E Carreño, RL Johnston… - American journal of …, 2014 - Elsevier
Purpose To identify clinical outcomes and treatment patterns of intravitreal dexamethasone
implant (Ozurdex; Allergan, Inc) in noninfectious uveitis in the clinical setting. Design …

Real-world assessment of intravitreal dexamethasone implant (0.7 mg) in patients with macular edema: the CHROME study

WC Lam, DA Albiani, P Yoganathan… - Clinical …, 2015 - Taylor & Francis
Background The purpose of this study was to evaluate the real-world use, efficacy, and
safety of one or more dexamethasone intravitreal implant (s) 0.7 mg (DEX implant) in …

Ocular biocompatibility of dexamethasone acetate loaded poly (ɛ-caprolactone) nanofibers

GR Da Silva, TH Lima, GM Fernandes-Cunha… - European Journal of …, 2019 - Elsevier
Electrospinning technique has been explored to produce nanofibers incorporated with drugs
as alternative drug delivery systems for therapeutic purposes in various organs and tissues …

Dexamethasone inserts in noninfectious uveitis: a single-center experience

D Pohlmann, GA Vom Brocke, S Winterhalter, T Steurer… - Ophthalmology, 2018 - Elsevier
Purpose To report the effectiveness of repeated intravitreal dexamethasone (DEX) inserts in
noninfectious uveitis patients. Design Prospective, single-center, interventional clinical trial …

[HTML][HTML] Intravitreal dexamethasone implants facilitate the management of refractory Behçet's uveitis with vasculitis

T Tao, S Yang, D He, Z Li, B Chen, L Zhu, W Su - Clinical Immunology, 2023 - Elsevier
To investigate the efficacy and safety of dexamethasone (DEX) implant, Ozurdex®, as an
adjunctive treatment for refractory Behçet's uveitis (BU), a total of 61 patients (80 eyes) were …

New therapies in development for the management of non‐infectious uveitis: a review

M Hassan, S Karkhur, JH Bae, MS Halim… - Clinical & …, 2019 - Wiley Online Library
Uveitis is a spectrum of inflammatory disorders characterized by ocular inflammation and is
one of the leading causes of preventable visual loss. The main aim of the treatment of uveitis …

Dexamethasone Intravitreal Implant (OZURDEX®) for Macular Edema Secondary to Noninfectious Uveitis: a Review of the Literature

H Massa, P Georgoudis, GD Panos - Therapeutic delivery, 2019 - Taylor & Francis
Macular edema (ME) is the leading cause of visual loss in uveitis and may persist long after
ocular inflammation has been resolved. Local steroids are the first line treatment for uveitis …