Recent advances in droplet microfluidics for single-cell analysis

Z Jiang, H Shi, X Tang, J Qin - TrAC Trends in Analytical Chemistry, 2023 - Elsevier
Single-cell manipulation and analysis is essential for studying many fundamental biological
processes and discovering cellular heterogeneity. Multi-parameter studies of intercellular …

Droplet-based microfluidics in biomedical applications

L Amirifar, M Besanjideh, R Nasiri, A Shamloo… - …, 2022 - iopscience.iop.org
Droplet-based microfluidic systems have been employed to manipulate discrete fluid
volumes with immiscible phases. Creating the fluid droplets at microscale has led to a …

Single-cell droplet microfluidics for biomedical applications

D Liu, M Sun, J Zhang, R Hu, W Fu, T Xuanyuan, W Liu - Analyst, 2022 - pubs.rsc.org
Single-cell manipulation and analysis is critical to the study of many fundamental biological
processes and uncovering cellular heterogeneity, and presents the potential for extremely …

Recent advances in microfluidic platforms for single-cell analysis in cancer biology, diagnosis and therapy

H Tavakoli, W Zhou, L Ma, S Perez, A Ibarra… - TrAC Trends in …, 2019 - Elsevier
Understanding molecular, cellular, genetic and functional heterogeneity of tumors at the
single-cell level has become a major challenge for cancer research. The microfluidic …

The vision of point-of-care PCR tests for the COVID-19 pandemic and beyond

H Zhu, H Zhang, S Ni, M Korabečná, L Yobas… - TrAC Trends in …, 2020 - Elsevier
Infectious diseases, such as the most recent case of coronavirus disease 2019, have
brought the prospect of point-of-care (POC) diagnostic tests into the spotlight. A rapid …

Microfluidic single‐cell omics analysis

X Xu, J Wang, L Wu, J Guo, Y Song, T Tian, W Wang… - Small, 2020 - Wiley Online Library
The commonly existing cellular heterogeneity plays a critical role in biological processes
such as embryonic development, cell differentiation, and disease progress. Single‐cell …

Micro-engineering and nano-engineering approaches to investigate tumour ecosystems

M Kim, M Panagiotakopoulou, C Chen, SB Ruiz… - Nature Reviews …, 2023 - nature.com
The interactions among tumour cells, the tumour microenvironment (TME) and non-tumour
tissues are of interest to many cancer researchers. Micro-engineering approaches and …

Recent advances in single cell manipulation and biochemical analysis on microfluidics

D Gao, F **, M Zhou, Y Jiang - Analyst, 2019 - pubs.rsc.org
Single cell analysis has become of great interest with unprecedented capabilities for the
systematic investigation of cell-to-cell variation in large populations. Rapid and multi …

Digital polymerase chain reaction technology–recent advances and future perspectives

KR Sreejith, CH Ooi, J **, DV Dao, NT Nguyen - Lab on a Chip, 2018 - pubs.rsc.org
Digital polymerase chain reaction (dPCR) technology has remained a “hot topic” in the last
two decades due to its potential applications in cell biology, genetic engineering, and …

[HTML][HTML] Recent advancements in microfluidic-based biosensors for detection of genes and proteins: Applications and techniques

S Siavashy, M Soltani, S Rahimi, M Hosseinali… - … and Bioelectronics: X, 2024 - Elsevier
This article has tried to provide an overview of the most sophisticated microfluidic biosensors
for identifying nucleic acids and proteins at the site of treatment. Microfluidics, which also …