Synthetic alternatives to Matrigel
EA Aisenbrey, WL Murphy - Nature Reviews Materials, 2020 - nature.com
Matrigel, a basement-membrane matrix extracted from Engelbreth–Holm–Swarm mouse
sarcomas, has been used for more than four decades for a myriad of cell-culture …
sarcomas, has been used for more than four decades for a myriad of cell-culture …
Impact of cryopreservation and freeze-thawing on therapeutic properties of mesenchymal stromal/stem cells and other common cellular therapeutics
C Cottle, AP Porter, A Lipat, C Turner-Lyles… - Current stem cell …, 2022 - Springer
Abstract Purpose of Review Cryopreservation and its associated freezing and thawing
procedures–short “freeze-thawing”–are among the final steps in economically viable …
procedures–short “freeze-thawing”–are among the final steps in economically viable …
Cellular reprogramming and epigenetic rejuvenation
Ageing is an inevitable condition that afflicts all humans. Recent achievements, such as the
generation of induced pluripotent stem cells, have delivered preliminary evidence that …
generation of induced pluripotent stem cells, have delivered preliminary evidence that …
[HTML][HTML] Cardiovascular disease models: a game changing paradigm in drug discovery and screening
H Savoji, MH Mohammadi, N Rafatian, MK Toroghi… - Biomaterials, 2019 - Elsevier
Cardiovascular disease is the leading cause of death worldwide. Although investment in
drug discovery and development has been sky-rocketing, the number of approved drugs has …
drug discovery and development has been sky-rocketing, the number of approved drugs has …
Effect of Freeze‐Drying on Apple Pomace and Pomegranate Peel Powders Used as a Source of Bioactive Ingredients for the Development of Functional Yogurt
Agro‐industrial by‐products of fruits have turned into an essential source of bioactive
products. This study examined the effect of freeze‐drying on apple pomace powder (APP) …
products. This study examined the effect of freeze‐drying on apple pomace powder (APP) …
MSCs vs. iPSCs: Potential in therapeutic applications
K Thanaskody, AS Jusop, GJ Tye… - Frontiers in Cell and …, 2022 - frontiersin.org
Over the past 2 decades, mesenchymal stem cells (MSCs) have attracted a lot of interest as
a unique therapeutic approach for a variety of diseases. MSCs are capable of self-renewal …
a unique therapeutic approach for a variety of diseases. MSCs are capable of self-renewal …
The potential and limitations of induced pluripotent stem cells to achieve wound healing
J Gorecka, V Kostiuk, A Fereydooni, L Gonzalez… - Stem cell research & …, 2019 - Springer
Wound healing is the physiologic response to a disruption in normal skin architecture and
requires both spatial and temporal coordination of multiple cell types and cytokines. This …
requires both spatial and temporal coordination of multiple cell types and cytokines. This …
Partial reprogramming induces a steady decline in epigenetic age before loss of somatic identity
Induced pluripotent stem cells (IPSCs), with their unlimited regenerative capacity, carry the
promise for tissue replacement to counter age‐related decline. However, attempts to realize …
promise for tissue replacement to counter age‐related decline. However, attempts to realize …
Therapeutic potential of stem cells in regeneration of liver in chronic liver diseases: Current perspectives and future challenges
The deposition of extracellular matrix and hyperplasia of connective tissue characterizes
chronic liver disease called hepatic fibrosis. Progression of hepatic fibrosis may lead to …
chronic liver disease called hepatic fibrosis. Progression of hepatic fibrosis may lead to …
Brain-on-a-chip: A history of development and future perspective
Since the advent of organ-on-a-chip, many researchers have tried to mimic the physiology of
human tissue on an engineered platform. In the case of brain tissue, structural connections …
human tissue on an engineered platform. In the case of brain tissue, structural connections …