Background The mucins found as components of mucus gel layers at mucosal surfaces
throughout the body play roles in protection as part of the defensive barrier on an organ and …

Mucin type O‐glycosylation is one of the most diverse types of glycosylation, playing
essential roles in tissue development and homeostasis. In complex organisms, O‐GalNAc …

Mucins are a large family of heavily O-glycosylated proteins that cover all mucosal surfaces
and constitute the major macromolecules in most body fluids. Mucins are primarily defined …

Advances in nuclease-based gene-editing technologies have enabled precise, stable, and
systematic genetic engineering of glycosylation capacities in mammalian cells, opening up a …

In the last decade, carbohydrate microarrays have been core technologies for analyzing
carbohydrate-mediated recognition events in a high-throughput fashion. A number of …

IgA nephropathy, initially described in 1968 as a kidney disease with glomerular
“intercapillary deposits of IgA-IgG”, has no disease-specific treatment and is a common …

Based on important cell-biological and biochemical results concerning the structural
difference between membrane glycoproteins of normal epithelial cells and epithelial tumour …

Purpose: Adhesion of disseminating tumor cells to the blood vascular endothelium is a
pivotal step in metastasis. Previous investigations have shown that galectin-3 concentrations …

Introduction Detection of serum biomarkers for early diagnosis of breast cancer remains an
important goal. Changes in the structure of O-linked glycans occur in all breast cancers …

Glycosyltransferases are useful synthetic tools for the preparation of natural
oligosaccharides, glycoconjugates and their analogues. High expression levels of …