Nuclear factor of activated T cells (NFAT) was first identified as a transcription factor about 3
decades ago and was not well studied until the development of immunosuppressant …

Animals abandoned their marine niche and successfully adapted to life on land multiple
times throughout evolution, providing a rare opportunity to study the mechanisms driving …

In euryhaline fish, prolactin (Prl) plays an essential role in freshwater (FW) acclimation. In the
euryhaline and eurythermal Mozambique tilapia, Oreochromis mossambicus, Prl cells are …

Land-based recirculating aquaculture systems (RAS) have risen in prevalence in recent
years for Atlantic salmon production, enabling intensive production which allows increased …

In euryhaline fish, prolactin (Prl) plays a key role in freshwater acclimation. Prl release in the
rostral pars distalis (RPD) of the pituitary is directly stimulated by a fall in extracellular …

Euryhaline tilapia (Oreochromis mossambicus) are fish that tolerate a wide salinity range
from fresh water to> 3× seawater. Even though the physiological effector mechanisms of …

Euryhaline fish experience variable osmotic environments requiring physiological
adjustments to tolerate elevated salinity. Mozambique tilapia (Oreochromis mossambicus) …

Summer mortality is a phenomenon associated with high temperature water spikes that can
result in mass mortalities of abalone and other molluscs. This is a particular concern for …

The developmental transition of juvenile salmon from a freshwater resident morph (parr) to a
seawater (SW) migratory morph (smolt), known as smoltification, entails a reorganization of …

In this thesis, I investigated the molecular mechanisms underlying the transduction of two
fundamental sensory modalities, osmoreception and thermosensitivity, in fish. The scope …