Physics of cell adhesion: some lessons from cell-mimetic systems

E Sackmann, AS Smith - Soft matter, 2014 - pubs.rsc.org
Cell adhesion is a paradigm of the ubiquitous interplay of cell signalling, modulation of
material properties and biological functions of cells. It is controlled by competition of short …

[HTML][HTML] Scale-independent roughness value of cell membranes studied by means of AFM technique

PD Antonio, M Lasalvia, G Perna, V Capozzi - Biochimica et Biophysica …, 2012 - Elsevier
The roughness of cell membrane is a very interesting indicator of cell's health state. Atomic
Force Microscopy allows us to investigate the roughness of cell membrane in great detail …

First-principle coarse-graining framework for scale-free bell-like association and dissociation rates in thermal and active systems

JA Janeš, C Monzel, D Schmidt, R Merkel, U Seifert… - Physical Review X, 2022 - APS
Fluctuations of surfaces that harbor reactive molecules interacting across the intervening
space strongly influence the reaction kinetics. One such paradigmatic system is the cell …

Nucleation of ligand-receptor domains in membrane adhesion

T Bihr, U Seifert, AS Smith - Physical review letters, 2012 - APS
We present a comprehensive model for the nucleation of domains in membrane adhesion.
We determine the critical number of bonds in a nucleus and calculate the probability …

Model for probing membrane-cortex adhesion by micropipette aspiration and fluctuation spectroscopy

R Alert, J Casademunt, J Brugués, P Sens - Biophysical journal, 2015 - cell.com
We propose a model for membrane-cortex adhesion that couples membrane deformations,
hydrodynamics, and kinetics of membrane-cortex ligands. In its simplest form, the model …

Multiscale approaches to protein-mediated interactions between membranes—relating microscopic and macroscopic dynamics in radially growing adhesions

T Bihr, U Seifert, AS Smith - New journal of physics, 2015 - iopscience.iop.org
Macromolecular complexation leading to coupling of two or more cellular membranes is a
crucial step in a number of biological functions of the cell. While other mechanisms may also …

Atomic force microscopy reveals new biophysical markers for monitoring subcellular changes in oxidative injury: Neuroprotective effects of quercetin at the nanoscale

M Jazvinšćak Jembrek, J Vlainić, V Čadež, S Šegota - PLoS One, 2018 - journals.plos.org
Oxidative stress has been recognised as an important pathological mechanism underlying
the development of neurodegenerative diseases. The biomarkers for assessing the degree …

Signature of a nonharmonic potential as revealed from a consistent shape and fluctuation analysis of an adherent membrane

D Schmidt, C Monzel, T Bihr, R Merkel, U Seifert… - Physical Review X, 2014 - APS
The interaction of fluid membranes with a scaffold, which can be a planar surface or a more
complex structure, is intrinsic to a number of systems from artificial supported bilayers and …

Equilibrium modeling of the mechanics and structure of the cancer glycocalyx

JG Gandhi, DL Koch, MJ Paszek - Biophysical Journal, 2019 - cell.com
The glycocalyx is a thick coat of proteins and carbohydrates on the outer surface of all
eukaryotic cells. Overproduction of large, flexible or rod-like biopolymers, including …

[PDF][PDF] 3D scanning probe nanotomography of tissue spheroid fibroblasts interacting with electrospun polyurethane scaffold

AE Efimov, OI Agapova, LA Safonova… - Express Polymer …, 2019 - researchgate.net
We present a 3D study of nanostructural features of a bioprinted tissue spheroid interacting
with polyurethane dual-scale biocompatible scaffold manufactured by three-dimensional …