Translating 3D printed pharmaceuticals: From hype to real-world clinical applications
Abstract Three-dimensional (3D) printing is a revolutionary technology that is disrupting
pharmaceutical development by enabling the production of personalised printlets (3D …
pharmaceutical development by enabling the production of personalised printlets (3D …
Commercially available enteric empty hard capsules, production technology and application
A Franc, D Vetchý, N Fülöpová - Pharmaceuticals, 2022 - mdpi.com
Currently, there is a growing need to prepare small batches of enteric capsules for individual
therapy or clinical evaluation since many acidic-sensitive substances should be protected …
therapy or clinical evaluation since many acidic-sensitive substances should be protected …
[HTML][HTML] Visualizing disintegration of 3D printed tablets in humans using MRI and comparison with in vitro data
I Seoane-Viano, T Pérez-Ramos, J Liu… - Journal of Controlled …, 2024 - Elsevier
Abstract Three-dimensional (3D) printing is revolutionising the way that medicines are
manufactured today, paving the way towards more personalised medicine. However, there …
manufactured today, paving the way towards more personalised medicine. However, there …
Enhanced oral bioavailability and neuroprotective effect of fisetin through its SNEDDS against rotenone-induced Parkinson's disease rat model
Fisetin (FS) was reported to have various pharmacological activities. But due to its lower
aqueous solubility and oral bioavailability, it is not in much use. As solubility and …
aqueous solubility and oral bioavailability, it is not in much use. As solubility and …
3D printed tacrolimus rectal formulations ameliorate colitis in an experimental animal model of inflammatory bowel disease
I Seoane-Viaño, N Gómez-Lado, H Lázare-Iglesias… - Biomedicines, 2020 - mdpi.com
The aim of this study was to fabricate novel self-supporting tacrolimus suppositories using
semisolid extrusion 3-dimensional printing (3DP) and to investigate their efficacy in an …
semisolid extrusion 3-dimensional printing (3DP) and to investigate their efficacy in an …
A wireless, ingestible pH sensing capsule system based on iridium oxide for monitoring gastrointestinal health
The pH of the gastrointestinal (GI) tract has strong correlation with many GI diseases. In this
study, a wireless and ingestible capsule system for monitoring GI pH was reported. Iridium …
study, a wireless and ingestible capsule system for monitoring GI pH was reported. Iridium …
Inhibition of urease-mediated ammonia production by 2-octynohydroxamic acid in hepatic encephalopathy
Hepatic encephalopathy is a neuropsychiatric complication of liver disease which is partly
associated with elevated ammonemia. Urea hydrolysis by urease-producing bacteria in the …
associated with elevated ammonemia. Urea hydrolysis by urease-producing bacteria in the …
A self-unfolding proximity enabling device for oral delivery of macromolecules
M Ghavami, J Pedersen, RB Kjeldsen… - … Clinics and Research, 2023 - journals.lww.com
Oral delivery of macromolecules remains highly challenging due to their rapid degradation
in the gastrointestinal tract and poor absorption across the tight junctions of the epithelium …
in the gastrointestinal tract and poor absorption across the tight junctions of the epithelium …
Effect of co-administration of probiotics with guar gum, pectin and eudragit S100 based colon targeted mini tablets containing 5-Fluorouracil for site specific release
Oral colon targeted mini-tablets containing 5-Fluorouracil (5-FU) were developed by using
guar gum, pectin and Eudragit S100. Probiotics were co-administered to constantly …
guar gum, pectin and Eudragit S100. Probiotics were co-administered to constantly …
Anaesthesia by intravenous propofol reduces the incidence of intra-operative gastric electrical slow-wave dysrhythmias compared to isoflurane
Gastric motility is coordinated by bioelectrical slow-wave activity, and abnormal electrical
dysrhythmias have been associated with nausea and vomiting. Studies have often been …
dysrhythmias have been associated with nausea and vomiting. Studies have often been …