Background Nowadays, conventional medical treatments such as surgery, radiotherapy, and
chemotherapy cannot cure all types of cancer. A promising approach to treat solid tumors is …

Tumor-associated macrophages (TAMs) exert integrated effects in all aspects of tumor
progression, including tumor cell proliferation, angiogenesis, invasion, and metastasis …

Immunotherapeutic treatment approaches are now an integral part of the treatment of many
solid tumors. However, attempts to integrate immunotherapy into the treatment of prostate …

Background Prostate cancer (PCa) is the second most common malignancy in men
worldwide. Growing evidence substantiates the important role of immunotherapy in human …

Currently, tumor treatment research still focuses on the cancer cells themselves, but the fact
that the immune system plays an important role in inhibiting tumor development cannot be …

Novel therapeutic agents in clinical trials offer a paradigm shift in the approach to battling
this prevalent and destructive disease, and the area of cancer therapy is on the precipice of …

Background: In advanced bladder cancer (BCa), platinum-based chemotherapy represents
the first-choice treatment. In the last ten years, immune checkpoint inhibitors (ICIs) have …

Simple Summary Although immune check point inhibitors have been established as a new
paradigm in cancer treatment, they have shown no clinical benefit in immune excluded or …

Due to its slow progression and susceptibility to radical forms of treatment, low-grade PC is
associated with high overall survival (OS). With the clinical progression of PC, the therapy is …

Background This phase 1 study evaluated PF-06753512, a vaccine-based immunotherapy
regimen (PrCa VBIR), in two clinical states of prostate cancer (PC), metastatic castration …