Non-invasive biomedical research and diagnostics enabled by innovative compact lasers

KS Litvinova, IE Rafailov, AV Dunaev… - Progress in Quantum …, 2017 - Elsevier
For over half a century, laser technology has undergone a technological revolution. These
technologies, particularly semiconductor lasers, are employed in a myriad of fields. Optical …

Laser-based non-invasive spectrophotometry–An overview of possible medical applications: Laser-basierte, nicht-invasive Spektralphotometrie–Übersicht über …

D Rogatkin, V Shumskiy, S Tereshenko… - Photonics & Lasers in …, 2013 - degruyter.com
Background and objective: The problem of the medical application of non-invasive (in vivo,
in situ) laser diagnostics, based on the principles of spectrophotometry and laser spectral …

Investigating tissue respiration and skin microhaemocirculation under adaptive changes and the synchronization of blood flow and oxygen saturation rhythms

AV Dunaev, VV Sidorov, AI Krupatkin… - Physiological …, 2014 - iopscience.iop.org
Multi-functional laser non-invasive diagnostic systems allow the study of a number of
microcirculatory parameters, including index of blood microcirculation (I m)(by laser Doppler …

Individual variability analysis of fluorescence parameters measured in skin with different levels of nutritive blood flow

AV Dunaev, VV Dremin, EA Zherebtsov… - Medical engineering & …, 2015 - Elsevier
Fluorescence spectroscopy has recently become more common in clinical medicine.
However, there are still many unresolved issues related to the methodology and …

How the melanin concentration in the skin affects the fluorescence-spectroscopy signal formation

VV Dremin, AV Dunaev - Journal of Optical Technology, 2016 - opg.optica.org
The influence of various melanin concentrations on the endogenous fluorescence intensity
of biological tissue has been experimentally studied, and the fluorescence signals have …

Substantiation of medical and technical requirements for noninvasive spectrophotometric diagnostic devices

AV Dunaev, EA Zherebtsov… - Journal of …, 2013 - spiedigitallibrary.org
A scientific approach to the formulation of medical and technical requirements (MTRs) for
noninvasive spectrophotometric diagnostic devices using optical technologies such as laser …

The development of attenuation compensation models of fluorescence spectroscopy signals

VV Dremin, EA Zherebtsov, IE Rafailov… - … Fall Meeting 2015 …, 2016 - spiedigitallibrary.org
This study examines the effect of blood absorption on the endogenous fluorescence signal
intensity of biological tissues. Experimental studies were conducted to identify these effects …

Мультимодальная оптическая диагностика микроциркуляторно-тканевых систем организма человека

АВ Дунаев - 2022 - elibrary.ru
В монографии рассматривается методология мультимодальной оптической
диагностики для оценки функционального состояния микроциркуляторно-тканевых …

Laser reflectance oximetry and Doppler flowmetry in assessment of complex physiological parameters of cutaneous blood microcirculation

AV Dunaev, VV Sidorov, NA Stewart… - Advanced …, 2013 - spiedigitallibrary.org
The integration of multiple optical techniques within a single diagnostic device is used to
address the difficulties in standardising measurement of cutaneous blood micro-dynamics …

In vivo noninvasive measurement of skin autofluorescence biomarkers relate to cardiovascular disease in mice

N Akbar, S Sokolovski, A Dunaev… - Journal of …, 2014 - Wiley Online Library
Background and objective The formation of reactive oxygen species (ROS) is associated
with cardiovascular disease (CVD). High dietary cholesterol can significantly alter the …