The field of psychiatry is hampered by a lack of robust, reliable and valid biomarkers that can
aid in objectively diagnosing patients and providing individualized treatment …

Mental ill health, which has been the leading health and social issue impacting the lives and
futures of young people for decades, has entered a dangerous phase. Accumulating …

Background Schizophrenia is a common, severe, and usually chronic disorder. Maintenance
treatment with antipsychotic drugs can prevent relapse but also causes side-effects. We …

Abstract Purpose of Review We review recent developments on risk factors in
schizophrenia. Recent Findings The way we think about schizophrenia today is profoundly …

Background Emraclidine is a novel, brain-penetrant, highly selective M4 receptor positive
allosteric modulator in development for the treatment of schizophrenia. We aimed to …

Objectives: This guideline provides recommendations for the clinical management of
schizophrenia and related disorders for health professionals working in Australia and New …

With a political debate about the potential risks and benefits of cannabis use as a backdrop,
the wave of legalization and liberalization initiatives continues to spread. Four states …

The idea that a longer duration of untreated psychosis (DUP) leads to poorer outcomes has
contributed to extensive changes in mental health services worldwide and has attracted …

The long‐term benefit‐to‐risk ratio of sustained antipsychotic treatment for schizophrenia
has recently been questioned. In this paper, we critically examine the literature on the long …

Schizophrenia remains a major burden on patients and society. The dopamine hypothesis
attempts to explain the pathogenic mechanisms of the disorder, and the …