Circadian disruption, clock genes, and metabolic health

LA Schrader, SM Ronnekleiv-Kelly… - The Journal of Clinical …, 2024 - jci.org
A growing body of research has identified circadian-rhythm disruption as a risk factor for
metabolic health. However, the underlying biological basis remains complex, and complete …

Dietary regulation in health and disease

Q Wu, ZJ Gao, X Yu, P Wang - Signal Transduction and Targeted …, 2022 - nature.com
Nutriments have been deemed to impact all physiopathologic processes. Recent evidences
in molecular medicine and clinical trials have demonstrated that adequate nutrition …

[HTML][HTML] Late isocaloric eating increases hunger, decreases energy expenditure, and modifies metabolic pathways in adults with overweight and obesity

N Vujović, MJ Piron, J Qian, SL Chellappa… - Cell metabolism, 2022 - cell.com
Late eating has been linked to obesity risk. It is unclear whether this is caused by changes in
hunger and appetite, energy expenditure, or both, and whether molecular pathways in …

Kee** an eye on circadian time in clinical research and medicine

EB Klerman, A Brager, MA Carskadon… - Clinical and …, 2022 - Wiley Online Library
Background Daily rhythms are observed in humans and almost all other organisms. Most of
these observed rhythms reflect both underlying endogenous circadian rhythms and evoked …

Complex physiology and clinical implications of time-restricted eating

MC Petersen, MR Gallop, SF Ramos… - Physiological …, 2022 - journals.physiology.org
Time-restricted eating (TRE) is a dietary intervention that limits food consumption to a
specific time window each day. The effect of TRE on body weight and physiological …

Desynchronizing the sleep–wake cycle from circadian timing to assess their separate contributions to physiology and behaviour and to estimate intrinsic circadian …

W Wang, RK Yuan, JF Mitchell, KM Zitting… - Nature protocols, 2023 - nature.com
Circadian clocks drive cyclic variations in many aspects of physiology, but some daily
variations are evoked by periodic changes in the environment or sleep–wake state and …

Interplay of Dinner Timing and MTNR1B Type 2 Diabetes Risk Variant on Glucose Tolerance and Insulin Secretion: A Randomized Crossover Trial

M Garaulet, J Lopez-Minguez, HS Dashti… - Diabetes …, 2022 - Am Diabetes Assoc
OBJECTIVE We tested whether the concurrence of food intake and elevated concentrations
of endogenous melatonin, as occurs with late eating, results in impaired glucose control, in …

The sleep–circadian interface: A window into mental disorders

N Meyer, R Lok, C Schmidt, SD Kyle… - Proceedings of the …, 2024 - National Acad Sciences
Sleep, circadian rhythms, and mental health are reciprocally interlinked. Disruption to the
quality, continuity, and timing of sleep can precipitate or exacerbate psychiatric symptoms in …

Interorgan rhythmicity as a feature of healthful metabolism

J Bass - Cell metabolism, 2024 - cell.com
The finding that animals with circadian gene mutations exhibit diet-induced obesity and
metabolic syndrome with hypoinsulinemia revealed a distinct role for the clock in the brain …

[HTML][HTML] Effects of time-restricted eating with different eating duration on anthropometrics and cardiometabolic health: a systematic review and meta-analysis

MK Zaman, NIMF Teng, SS Kasim… - World Journal of …, 2023 - ncbi.nlm.nih.gov
BACKGROUND Time-restricted eating (TRE) is a dietary approach that limits eating to a set
number of hours per day. Human studies on the effects of TRE intervention on …