The role of cytochrome P450s in insect toxicology and resistance

R Nauen, C Bass, R Feyereisen… - Annual Review of …, 2022 - annualreviews.org
Insect cytochrome P450 monooxygenases (P450s) perform a variety of important
physiological functions, but it is their role in the detoxification of xenobiotics, such as natural …

[HTML][HTML] A review of the molecular mechanisms of acaricide resistance in mites and ticks

S De Rouck, E İnak, W Dermauw… - Insect Biochemistry and …, 2023 - Elsevier
Abstract The Arachnida subclass of Acari comprises many harmful pests that threaten
agriculture as well as animal health, including herbivorous spider mites, the bee parasite …

[HTML][HTML] Functional and structural diversity of insect glutathione S-transferases in xenobiotic adaptation

SK BK, T Moural, F Zhu - International journal of biological sciences, 2022 - ncbi.nlm.nih.gov
As a superfamily of multifunctional enzymes that is mainly associated with xenobiotic
adaptation, glutathione S-transferases (GSTs) facilitate insects' survival under chemical …

[HTML][HTML] The evolution of insecticide resistance in the peach potato aphid, Myzus persicae

C Bass, AM Puinean, CT Zimmer, I Denholm… - Insect biochemistry and …, 2014 - Elsevier
The peach potato aphid, Myzus persicae is a globally distributed crop pest with a host range
of over 400 species including many economically important crop plants. The intensive use of …

[HTML][HTML] The ABC gene family in arthropods: comparative genomics and role in insecticide transport and resistance

W Dermauw, T Van Leeuwen - Insect biochemistry and molecular biology, 2014 - Elsevier
About a 100 years ago, the Drosophila white mutant marked the birth of Drosophila genetics.
The white gene turned out to encode the first well studied ABC transporter in arthropods …

CYP6AE gene cluster knockout in Helicoverpa armigera reveals role in detoxification of phytochemicals and insecticides

H Wang, Y Shi, L Wang, S Liu, S Wu, Y Yang… - Nature …, 2018 - nature.com
The cotton bollworm Helicoverpa armigera, is one of the world's major pest of agriculture,
feeding on over 300 hosts in 68 plant families. Resistance cases to most insecticide classes …

The economic importance of acaricides in the control of phytophagous mites and an update on recent acaricide mode of action research

T Van Leeuwen, L Tirry, A Yamamoto, R Nauen… - Pesticide biochemistry …, 2015 - Elsevier
Acaricides are one of the cornerstones of an efficient control program for phytophagous
mites. An analysis of the global acaricide market reveals that spider mites such as …

A nuclear receptor HR96-related gene underlies large trans-driven differences in detoxification gene expression in a generalist herbivore

M Ji, M Vandenhole, B De Beer, S De Rouck… - Nature …, 2023 - nature.com
The role, magnitude, and molecular nature of trans-driven expression variation underlying
the upregulation of detoxification genes in pesticide resistant arthropod populations has …

Genotype to phenotype, the molecular and physiological dimensions of resistance in arthropods

R Feyereisen, W Dermauw, T Van Leeuwen - Pesticide biochemistry and …, 2015 - Elsevier
The recent accumulation of molecular studies on mutations in insects, ticks and mites
conferring resistance to insecticides, acaricides and biopesticides is reviewed. Resistance is …

Divergent amplifications of CYP9A cytochrome P450 genes provide two noctuid pests with differential protection against xenobiotics

Y Shi, Q Liu, W Lu, J Yuan, Y Yang… - Proceedings of the …, 2023 - National Acad Sciences
Here, we provide mechanistic support for the involvement of the CYP9A subfamily of
cytochrome P450 monooxygenases in the detoxification of host plant defense compounds …