Raman spectroscopy for chemical biology research

K Dodo, K Fujita, M Sodeoka - Journal of the American Chemical …, 2022‏ - ACS Publications
In chemical biology research, various fluorescent probes have been developed and used to
visualize target proteins or molecules in living cells and tissues, yet there are limitations to …

The emerging role of Raman spectroscopy as an omics approach for metabolic profiling and biomarker detection toward precision medicine

G Cutshaw, S Uthaman, N Hassan… - Chemical …, 2023‏ - ACS Publications
Omics technologies have rapidly evolved with the unprecedented potential to shape
precision medicine. Novel omics approaches are imperative toallow rapid and accurate data …

Bridging live-cell imaging and next-generation cancer treatment

M Alieva, AKL Wezenaar, EJ Wehrens… - Nature Reviews Cancer, 2023‏ - nature.com
By providing spatial, molecular and morphological data over time, live-cell imaging can
provide a deeper understanding of the cellular and signalling events that determine cancer …

Stimulated Raman photothermal microscopy toward ultrasensitive chemical imaging

Y Zhu, X Ge, H Ni, J Yin, H Lin, L Wang, Y Tan… - Science …, 2023‏ - science.org
Stimulated Raman scattering (SRS) microscopy has shown enormous potential in revealing
molecular structures, dynamics, and couplings in complex systems. However, the sensitivity …

From genotype to phenotype: Raman spectroscopy and machine learning for label-free single-cell analysis

Y Zhang, K Chang, B Ogunlade, L Herndon… - ACS …, 2024‏ - ACS Publications
Raman spectroscopy has made significant progress in biosensing and clinical research.
Here, we describe how surface-enhanced Raman spectroscopy (SERS) assisted with …

Miniaturized chemical tags for optical imaging

S Benson, F De Moliner, W Tip**… - Angewandte Chemie …, 2022‏ - Wiley Online Library
Recent advances in optical bioimaging have prompted the need for minimal chemical
reporters that can retain the molecular recognition properties and activity profiles of …

Quantitative stimulated Raman scattering microscopy: promises and pitfalls

B Manifold, D Fu - Annual Review of Analytical Chemistry, 2022‏ - annualreviews.org
Since its first demonstration, stimulated Raman scattering (SRS) microscopy has become a
powerful chemical imaging tool that shows promise in numerous biological and biomedical …

Engineering rational SERS nanotags for parallel detection of multiple cancer circulating biomarkers

Z Zhang, R Guan, J Li, Y Sun - Chemosensors, 2023‏ - mdpi.com
Precision cancer medicine necessitates a personalized treatment plan for each individual
patient. Given cancer's heterogeneity and dynamic nature, the plot of patient-specific …

Triple-bond vibrations: Emerging applications in energy and biological sciences

L Zhou, R Feng, W Zhang, F Gai - The Journal of Physical …, 2023‏ - ACS Publications
Triple bonds, such as that formed between two carbon atoms (ie, C≡ C) or that formed
between one carbon atom and one nitrogen atom (ie, C≡ N), afford unique chemical …

tetraplex immunophenoty** of cell surface proteomes via synthesized plasmonic nanotags and portable Raman spectroscopy

J Wang, KM Koo, M Trau - Analytical Chemistry, 2022‏ - ACS Publications
Multiplex immunophenoty** of cell surface proteomes is useful for cell characterization as
well as providing valuable information on a patient's physiological or pathological state …