Semaphorins are extracellular signaling proteins that are essential for the development and
maintenance of many organs and tissues. The more than 20-member semaphorin protein …

Simple Summary Since the targeting of a single pro-angiogenic factor fails to improve
oncological disease outcome, significant efforts have been made to identify new pro …

Neuronal growth cones navigate over long distances along specific pathways to find their
correct targets. The mechanisms and molecules that direct this pathfinding are the topics of …

The fourth edition of Fundamental Neuroscience reinvents itself as an engrossing and
comprehensive presentation of the discipline of neuroscience, from molecules to cognition …

The endothelial barrier strictly maintains vascular and tissue homeostasis, and therefore
modulates many physiological processes such as angiogenesis, immune responses, and …

The complex patterns of neuronal wiring in the adult nervous system depend on a series of
guidance events during neural development that establish a framework on which functional …

Semaphorins, originally discovered as guidance cues for develo** axons, are involved in
many processes that shape the nervous system during development, from neuronal …

Axons are guided along specific pathways by attractive and repulsive cues in the
extracellular environment. Genetic and biochemical studies have led to the identification of …

In addition to its expression on subsets of axons, grasshopper Semaphorin I (Sema I,
previously called Fasciclin [Fas] Iv) is expressed on an epithelial stripe in the limb bud …

Repulsive guidance cues can steer neuronal growth cones during development and prevent
mature axons from regenerating. We have identified a 100 kd glycoprotein in the chick brain …