Analysis of interactions responsible for vasopressin binding to human neurohypophyseal hormone receptors—molecular dynamics study of the activated receptor …

MJ Ślusarz, A Giełdoń, R Ślusarz… - Journal of Peptide …, 2006 - Wiley Online Library
Abstract Vasopressin (CYFQNCPRG‐NH2, AVP) is a semicyclic endogenous peptide, which
exerts a variety of biological effects in mammals. The main physiological roles of AVP are …

Molecular Docking-Based Study of Vasopressin Analogues Modified at Positions 2 and 3 with N-Methylphenylalanine:  Influence on Receptor-Bound Conformations …

MJ Ślusarz, E Sikorska, R Ślusarz… - Journal of Medicinal …, 2006 - ACS Publications
In this study, four cyclic vasopressin (CYFQNCPRG-NH2, AVP) analogues substituted at
positions 2 and 3 with four combinations of enantiomers of N-methylphenylalanine have …

Lactic acid-fermented by-product of Shochu distillery reduces anxiety behavior in Neuropeptide Y knockout zebrafish by the regulation of isotoin neuron

M Hibarino, E Aoki, Y Kubo, H Nagata, S Tateno… - Journal of Material …, 2024 - Springer
The development of techniques to reduce stress in the aquaculture industry is essential for
the good growth, low mortality, and high flesh quality of farmed fish. Shochu is a traditional …

Molecular dynamics simulation of human neurohypophyseal hormone receptors complexed with oxytocin—modeling of an activated state

MJ Ślusarz, R Ślusarz… - Journal of peptide science …, 2006 - Wiley Online Library
The neurohypophyseal hormone oxytocin (CYIQNCPLG‐NH2, OT) is involved in the control
of labor, secretion of milk and many social and behavioral functions via interaction with its …

Investigation of mechanism of desmopressin binding in vasopressin V2 receptor versus vasopressin V1a and oxytocin receptors: Molecular dynamics simulation of the …

MJ Ślusarz, R Ślusarz… - … : Original Research on …, 2006 - Wiley Online Library
The vasopressin V2 receptor (V2R) belongs to the Class AG protein–coupled receptors
(GPCRs). V2R is expressed in the renal collecting duct (CD), where it mediates the …

Study of new oxytocin antagonist barusiban (fe200 440) affinity toward human oxytocin receptor versus vasopressin V1A and V2 receptors–molecular dynamics …

MJ Ślusarz, A Giełdoń, R Ślusarz… - QSAR & …, 2005 - Wiley Online Library
The nonapeptide hormone oxytocin CYIQNCPLG‐NH2 (OT) controls birth, lactation and
other physiological functions in the mammals via stimulation of its receptor (OTR), a member …

Influence of bulky 3, 3′-diphenylalanine enantiomers replacing position 2 of AVP analogues on their conformations: NMR and molecular modeling studies

E Sikorska, A Kwiatkowska, D Sobolewski… - European journal of …, 2010 - Elsevier
In this paper we use NMR spectroscopy and molecular modeling to examine four
vasopressin analogues substituted with bulky 3, 3′-diphenylalanine (Dpa) …

Molecular dynamics of complexes of atosiban with neurohypophyseal receptors in the fully hydrated phospholipid bilayer

MJ Ślusarz, R Ślusarz, R Meadows… - QSAR & …, 2004 - Wiley Online Library
The aim of our research was to get insight into the molecular mechanism of binding
atosiban, a strong selective oxytocin (OT) antagonist by OT receptor (OTR) versus …

Conformational studies of highly potent 1‐aminocyclohexane‐1‐carboxylic acid substituted V2 vasopressin agonists

E Sikorska, R Ślusarz, B Lammek - The Journal of Peptide …, 2005 - Wiley Online Library
Conformational studies of three agonists of V2 receptor modified with 1‐aminocyclohexane‐
1‐carboxylic acid (Acc),[Acc2, DArg8] VP,[Acc3] AVP and [Cpa1, Acc3] AVP, using 2D NMR …

Analogue and conformational studies on peptides, hormones and other biologically active peptides

B Penke, G Tóth, G Váradi - 2007 - books.rsc.org
The sub-divisions and the basic structure of this Chapter remained unchanged compared to
previous volumes. Core references for this Chapter were obtained from the Chemical …