Macroimmunology: The drivers and consequences of spatial patterns in wildlife immune defence

DJ Becker, GF Albery, MK Kessler… - Journal of Animal …, 2020 - Wiley Online Library
The prevalence and intensity of parasites in wild hosts varies across space and is a key
determinant of infection risk in humans, domestic animals and threatened wildlife. Because …

Specific alleles at immune genes, rather than genome‐wide heterozygosity, are related to immunity and survival in the critically endangered Attwater's prairie‐chicken

ZW Bateson, SC Hammerly, JA Johnson… - Molecular …, 2016 - Wiley Online Library
The negative effects of inbreeding on fitness are serious concerns for populations of
endangered species. Reduced fitness has been associated with lower genome‐wide …

Genetic drift outweighs natural selection at toll‐like receptor (TLR) immunity loci in a re‐introduced population of a threatened species

CE Grueber, GP Wallis, IG Jamieson - Molecular Ecology, 2013 - Wiley Online Library
During population establishment, genetic drift can be the key driver of changes in genetic
diversity, particularly while the population is small. However, natural selection can also play …

Disease and freeways drive genetic change in urban bobcat populations

LEK Serieys, A Lea, JP Pollinger… - Evolutionary …, 2015 - Wiley Online Library
Urbanization profoundly impacts animal populations by causing isolation, increased
susceptibility to disease, and exposure to toxicants. Genetic effects include reduced effective …

The ecoimmunology of invasive species

TA White, SE Perkins - Functional Ecology, 2012 - Wiley Online Library
Invasive populations frequently harbour a reduced parasite community compared with their
native counterparts. The loss of regulating enemies may result in re‐allocation of resources …

Lack of genetic diversity across diverse immune genes in an endangered mammal, the Tasmanian devil (Sarcophilus harrisii)

KM Morris, B Wright, CE Grueber, C Hogg… - Molecular …, 2015 - Wiley Online Library
The T asmanian devil (S arcophilus harrisii) is threatened with extinction due to the spread
of devil facial tumour disease. Polymorphisms in immune genes can provide adaptive …

Drift, not selection, shapes toll‐like receptor variation among oceanic island populations

C Gonzalez‐Quevedo, LG Spurgin, JC Illera… - Molecular …, 2015 - Wiley Online Library
Understanding the relative role of different evolutionary forces in sha** the level and
distribution of functional genetic diversity among natural populations is a key issue in …

Pollinator loss causes rapid adaptive evolution of selfing and dramatically reduces genome-wide genetic variability

JW Busch, S Bodbyl-Roels, S Tusuubira, JK Kelly - Evolution, 2022 - academic.oup.com
Although selfing populations harbor little genetic variation limiting evolutionary potential, the
causes are unclear. We experimentally evolved large, replicate populations of Mimulus …

Toll-like receptor diversity in 10 threatened bird species: relationship with microsatellite heterozygosity

CE Grueber, GJ Knafler, TM King, AM Senior… - Conservation …, 2015 - Springer
Measuring individual-level heterozygosity in threatened species is one approach to
understanding and mitigating losses of genetic diversity and the role of inbreeding …

Immunogenetic heterogeneity in a widespread ungulate: the European roe deer (Capreolus capreolus)

E Quéméré, M Galan, JF Cosson, F Klein… - Molecular …, 2015 - Wiley Online Library
Understanding how immune genetic variation is shaped by selective and neutral processes
in wild populations is of prime importance in both evolutionary biology and epidemiology …