In vitro selection of aptamers and their applications

MC DeRosa, A Lin, P Mallikaratchy… - Nature Reviews …, 2023 - nature.com
The introduction of the in vitro evolution method known as SELEX (systematic evolution of
ligands by exponential enrichment) more than 30 years ago led to the conception of …

Advances and challenges in small‐molecule DNA aptamer isolation, characterization, and sensor development

H Yu, O Alkhamis, J Canoura, Y Liu… - Angewandte Chemie …, 2021 - Wiley Online Library
Aptamers are short oligonucleotides isolated in vitro from randomized libraries that can bind
to specific molecules with high affinity, and offer a number of advantages relative to …

Advanced materials in sorbent-based analytical sample preparation

E Torabi, A Abdar, N Lotfian, M Bazargan… - Coordination Chemistry …, 2024 - Elsevier
New advanced materials' potential as sorbents during the sample preparation process has
recently been highlighted by developments in contemporary analytical chemistry …

Advances in aptamers, and application of mycotoxins detection: A review

Y Fan, J Li, K Amin, H Yu, H Yang, Z Guo… - Food Research …, 2023 - Elsevier
Mycotoxin contamination in food products can easily cause serious health hazards and
economic losses to human beings. How to accurately detect and effectively control …

Aptamer-based biosensors for environmental monitoring

EM McConnell, J Nguyen, Y Li - Frontiers in chemistry, 2020 - frontiersin.org
Due to their relative synthetic and chemical simplicity compared to antibodies, aptamers
afford enhanced stability and functionality for the detection of environmental contaminants …

Critical evaluation of aptamer binding for biosensor designs

Y Zhao, K Yavari, J Liu - TrAC Trends in Analytical Chemistry, 2022 - Elsevier
Over the last three decades, numerous aptamer-based biosensors have been reported. The
basis of these sensors is the selective binding of target analytes by aptamers. In the last few …

[HTML][HTML] Current and future technologies for the detection of antibiotic-resistant bacteria

D Yamin, V Uskoković, AM Wakil, MD Goni… - Diagnostics, 2023 - mdpi.com
Antibiotic resistance is a global public health concern, posing a significant threat to the
effectiveness of antibiotics in treating bacterial infections. The accurate and timely detection …

Screening, identification, and application of nucleic acid aptamers applied in food safety biosensing

R Liu, F Zhang, Y Sang, I Katouzian, SM Jafari… - Trends in Food Science …, 2022 - Elsevier
Background Nucleic acid aptamers, defined as small functional nucleic acids that can
selectively bind to a specific target, have become one of the main bio-recognition elements …

Small-molecule binding aptamers: Selection strategies, characterization, and applications

A Ruscito, MC DeRosa - Frontiers in chemistry, 2016 - frontiersin.org
Aptamers are single-stranded, synthetic oligonucleotides that fold into 3-dimensional
shapes capable of binding non-covalently with high affinity and specificity to a target …

Aptamer-based point-of-care-testing for small molecule targets: From aptamers to aptasensors, devices and applications

L Zhao, L Li, Y Zhao, C Zhu, R Yang, M Fang… - TrAC Trends in Analytical …, 2023 - Elsevier
Point-of-care testing (POCT) represented the diagnosis performing at or near patient located
site, has extended applications in healthcare, environmental safety, or food quality with low …