Biomolecule-protected gold nanoclusters: synthesis and biomedical applications

D Hao, X Zhang, R Su, Y Wang, W Qi - Journal of Materials Chemistry …, 2023 - pubs.rsc.org
Gold nanoclusters (AuNCs) consist of a few to several hundred gold atoms with a core size
of less than 2 nm. Gold nanoclusters are among the most stable metal nanoclusters and …

A recent insight of applications of gold nanoparticles in glioblastoma multiforme therapy

S Qureshi, S Anjum, M Hussain, A Sheikh… - International Journal of …, 2024 - Elsevier
The application of gold nanoparticles (AuNPs) in cancer therapy, particularly targeted
therapy of glioblastoma multiforme (GBM), is an up-and-coming field of research that has …

Multistage-responsive clustered nanosystem to improve tumor accumulation and penetration for photothermal/enhanced radiation synergistic therapy

S Hua, J He, F Zhang, J Yu, W Zhang, L Gao, Y Li… - Biomaterials, 2021 - Elsevier
Develo** new strategies to overcome biological barriers and achieve efficient delivery of
therapeutic nanoparticles (NPs) is the key to achieve positive therapeutic outcomes in …

[HTML][HTML] Oxidative damage to mitochondria enhanced by ionising radiation and gold nanoparticles in cancer cells

F Tabatabaie, R Franich, B Feltis, M Geso - International journal of …, 2022 - mdpi.com
Gold nanoparticles (AuNP) can increase the efficacy of radiation therapy by sensitising
tumor cells to radiation damage. When used in combination with radiation, AuNPs enhance …

[HTML][HTML] Requirements for designing an effective metallic nanoparticle (NP)-boosted radiation therapy (RT)

I Tremi, E Spyratou, M Souli, EP Efstathopoulos… - Cancers, 2021 - mdpi.com
Simple Summary Recent advances in nanotechnology gave rise to trials with various types
of metallic nanoparticles (NPs) to enhance the radiosensitization of cancer cells while …

Application of nanomaterials in diagnosis and treatment of glioblastoma

S Yu, L Chen, H Xu, S Long, J Jiang, W Wei… - Frontiers in …, 2022 - frontiersin.org
Diagnosing and treating glioblastoma patients is currently hindered by several obstacles,
such as tumor heterogeneity, the blood-brain barrier, tumor complexity, drug efflux pumps …

Enhancing nanoparticle accumulation in two dimensional, three dimensional, and xenograft mouse cancer cell models in the presence of docetaxel

K Bromma, N Dos Santos, I Barta, A Alexander… - Scientific reports, 2022 - nature.com
Recent clinical trials show docetaxel (DTX), given in conjunction with radiation therapy (RT)
and androgen suppression, improves survival in high-risk prostate cancer. Addition of gold …

Intercomparison of radiosensitization induced by gold and iron oxide nanoparticles in human glioblastoma cells irradiated by 6 MV photons

DB Guerra, EMN Oliveira, AR Sonntag, P Sbaraine… - Scientific Reports, 2022 - nature.com
In this work, an intercomparison of sensitization effects produced by gold (GNP) and dextran-
coated iron oxide (SPION-DX) nanoparticles in M059J and U87 human glioblastoma cells …

[HTML][HTML] Catalase-gold nanoaggregates manipulate the tumor microenvironment and enhance the effect of low-dose radiation therapy by reducing hypoxia

A Najafi, M Keykhaee, MH Kazemi, MY Karimi… - Biomedicine & …, 2023 - Elsevier
Radiotherapy as a standard method for cancer treatment faces tumor recurrence and
antitumoral unresponsiveness. Suppressive tumor microenvironment (TME) and hypoxia are …

[HTML][HTML] Enhanced Cytotoxicity against a Pancreatic Cancer Cell Line Combining Radiation and Gold Nanoparticles

A Martins, BC Ferreira, MM Gaspar, S Vieira, J Lopes… - Pharmaceutics, 2024 - mdpi.com
The present work consisted of an exploratory study aiming to evaluate in vitro the potential of
AuNPs during Radiation Therapy (RT) in human pancreatic adenocarcinoma cells. AuNPs …