Selenium is an essential dietary component for animals including humans, and there is
increasing evidence for the efficacy of certain forms of selenium as cancer-chemopreventive …

Cellular responses to high glucose are numerous and varied but ultimately result in
functional changes and, often, cell death. High glucose induces oxidative and nitrosative …

抄録 The essential trace element selenium has long been considered to exhibit anti-diabetic
and insulin-mimetic properties, but recent epidemiological studies indicated supranutritional …

Selenium (Se) homeostasis is tightly related to carbohydrate and lipid metabolism, but its
possible roles in obesity development and in adipocyte metabolism are unclear. The …

Expression of the chitinase 3-like protein HC-gp39 (human cartilage glycoprotein 39) is
associated with conditions of increased matrix turnover and tissue remodelling. High levels …

Background Mitochondrial dysfunction is one of the major events responsible for activation
of neuronal cell death pathways during cerebral ischemia. Trace element selenium has …

Background 3. Comparison of Akt isoforms 3.1. Sequence comparison and expression
pattern 3.2. Phenotype of the knock-out mouse 4. Akt oncogenic activity and its role in …

The vascular complications of diabetes mellitus impose a huge burden on the management
of this disease. The higher incidence of cardiovascular complications and the unfavorable …

Selenium is an essential chemopreventive antioxidant element to oxidative stress, although
high concentrations of selenium induce toxic and oxidative effects on the human body …

Glutamate-induced cytotoxicity is partially mediated by enhanced oxidative stress. The
objectives of the present study are to determine the effects of glutamate on mitochondrial …