Few neoplastic diseases have undergone a transformation in a relatively short period like
chronic myeloid leukemia (CML) has in the last few years. In 1960, CML was the first cancer …

Because there are differing opinions regarding treatment of patients in the chronic phase of
chronic myeloid leukemia (CML), the American Society of Hematology convened an expert …

Three patients with hematologic relapse after bone marrow transplantation for chronic
myelogenous leukemia were treated with interferon α and transfusion of viable donor buffy …

Background Transplantation of blood or bone-marrow stem cells is the treatment of choice
for selected patients with chronic myeloid leukaemia (CML). Transplantation is used with …

Cyclophosphamide (CY) cardiotoxicity may be a lethal complication of bone marrow
transplantation. Previous echocardiographic studies have reported that left ventricular …

Data on 405 patients with chronic myelogenous leukemia who received bone marrow
transplants in chronic phase were analyzed for factors predictive of outcome. The 4-year …

The major bcr-abl fusion gene is presently seen as the hallmark of chronic myeloid leukemia
(CML) and presumably as the cause of its development. Accordingly, long-term …

New insights have emerged from maturing long-term academic and commercial clinical
trials regarding optimum management of chronic myeloid leukemia (CML). Velocity of …

In unrelated marrow transplantation, the benefit of matching class II HLA-DRB1 and DQB1
alleles of the donor and recipient is well documented. Little is known about the clinical …

With the deaths of Janet Rowley and John Goldman in December 2013, the world lost two
pioneers in the field of chronic myeloid leukemia. In 1973, Janet Rowley, unraveled the …