Patient-specific inverse modeling of in vivo cardiovascular mechanics with medical image-derived kinematics as input data: concepts, methods, and applications

JH Bracamonte, SK Saunders, JS Wilson, UT Truong… - Applied Sciences, 2022 - mdpi.com
Inverse modeling approaches in cardiovascular medicine are a collection of methodologies
that can provide non-invasive patient-specific estimations of tissue properties, mechanical …

Effective data sampling strategies and boundary condition constraints of physics-informed neural networks for identifying material properties in solid mechanics

W Wu, M Daneker, MA Jolley, KT Turner… - Applied mathematics and …, 2023 - Springer
Material identification is critical for understanding the relationship between mechanical
properties and the associated mechanical functions. However, material identification is a …

Computational investigation of left ventricular hemodynamics following bioprosthetic aortic and mitral valve replacement

F Xu, EL Johnson, C Wang, A Jafari, CH Yang… - Mechanics Research …, 2021 - Elsevier
The left ventricle of the heart is a fundamental structure in the human cardiac system that
pumps oxygenated blood into the systemic circulation. Several valvular conditions can …

The actuator line method for wind turbine modelling applied in a variational multiscale framework

M Ravensbergen, AB Mohamed, A Korobenko - Computers & Fluids, 2020 - Elsevier
The actuator line method is implemented into a residual-based variational multiscale (VMS)
fluid modelling framework to simulate airflow around a wind turbine. In the actuator line …

A detailed mechanical and microstructural analysis of ovine tricuspid valve leaflets

WD Meador, M Mathur, GP Sugerman, T Jazwiec… - Acta biomaterialia, 2020 - Elsevier
The tricuspid valve ensures unidirectional blood flow from the right atrium to the right
ventricle. The three tricuspid leaflets operate within a dynamic stress environment of shear …

Parameterization, geometric modeling, and isogeometric analysis of tricuspid valves

EL Johnson, DW Laurence, F Xu, CE Crisp… - Computer methods in …, 2021 - Elsevier
Approximately 1.6 million patients in the United States are affected by tricuspid valve
regurgitation, which occurs when the tricuspid valve does not close properly to prevent …

Variational multiscale framework for cavitating flows

A Bayram, A Korobenko - Computational Mechanics, 2020 - Springer
A numerical formulation for the modeling of turbulent cavitating flows is presented. The flow
field is governed by the 3D, time-dependent Navier–Stokes equations for a compressible …

Integration of polarized spatial frequency domain imaging (pSFDI) with a biaxial mechanical testing system for quantification of load-dependent collagen architecture …

SV Jett, LT Hudson, R Baumwart, BN Bohnstedt, A Mir… - Acta biomaterialia, 2020 - Elsevier
Collagen fiber networks provide the structural strength of tissues, such as tendons, skin and
arteries. Quantifying the fiber architecture in response to mechanical loads is essential …

The tricuspid valve also maladapts as shown in sheep with biventricular heart failure

WD Meador, M Mathur, GP Sugerman, M Malinowski… - Elife, 2020 - elifesciences.org
Over 1.6 million Americans suffer from significant tricuspid valve leakage. In most cases this
leakage is designated as secondary. Thus, valve dysfunction is assumed to be due to valve …

A pilot in silico modeling‐based study of the pathological effects on the biomechanical function of tricuspid valves

DW Laurence, EL Johnson, MC Hsu… - International Journal …, 2020 - Wiley Online Library
Current clinical assessment of functional tricuspid valve regurgitation relies on metrics
quantified from medical imaging modalities. Although these clinical methodologies are …