Deep brain stimulation (DBS) has emerged as a promising treatment for select patients with
refractory major depressive disorder (MDD). The clinical effectiveness of DBS for MDD has …

Although deep brain stimulation (DBS) is an established treatment choice for Parkinson's
disease (PD), essential tremor and movement disorders, its effectiveness for the …

Deep brain stimulation (DBS) is an approved therapy for the treatment of medically refractory
and severe movement disorders. However, most existing neurostimulators can only apply …

Background Deep brain stimulation is increasingly being used for treatment‐resistant
depression. Blinded, randomized controlled trials of active versus sham treatment have …

Deep brain stimulation (DBS) is a last-resort treatment for neurological and psychiatric
disorders that are refractory to standard treatment. Over the last decades, the progress of …

Depression is characterized by impairments in adult neurogenesis. Reduced hippocampal
function, which is suggestive of neurogenesis impairments, is associated with depression …

Background Deep brain stimulation (DBS) has been applied in treatment-resistant
depression (TRD) as a putative intervention targeting different brain regions. However, the …

Major depressive disorder (MDD) is a disabling disease associated with profound functional
impairment. Cognitive deficits, increasingly recognised as a core feature of MDD, reduce …

Focal direct-to-brain neuromodulation approaches, such as repetitive transcranial magnetic
stimulation (TMS), deep brain stimulation (DBS) and ablative techniques, hold tremendous …

Abstract Background Cognitive symptoms in Major Depressive Disorder (MDD) are
persistent and commonly entail neurocognitive impairment and a decline in quality of life …