[HTML][HTML] The potential and controversy of targeting STAT family members in cancer

Y Verhoeven, S Tilborghs, J Jacobs, J De Waele… - Seminars in cancer …, 2020 - Elsevier
Abstract The Signal Transducer and Activator of Transcription (STAT) family of proteins
consists of transcription factors that play a complex and essential role in the regulation of …

[HTML][HTML] STAT1 in cancer: friend or foe?

Y Zhang, Z Liu - Discovery medicine, 2017 - discoverymedicine.com
The first STAT family member, STAT1, is an essential component of interferon (IFN)-
signaling, which mediates several cellular functions in response to stimulation by cytokines …

[HTML][HTML] Modified hyaluronic acid hydrogels with chemical groups that facilitate adhesion to host tissues enhance cartilage regeneration

J Chen, J Yang, L Wang, X Zhang, BC Heng… - Bioactive Materials, 2021 - Elsevier
Stable integration of hydrogel implants with host tissues is of critical importance to cartilage
tissue engineering. Designing and fabricating hydrogels with high adhesive strength …

Cytotoxicity of apigenin toward multiple myeloma cell lines and suppression of iNOS and COX-2 expression in STAT1-transfected HEK293 cells

AN Adham, S Abdelfatah, AM Naqishbandi… - Phytomedicine, 2021 - Elsevier
Background Apigenin is one of the most abundant dietary flavonoids that possesses multiple
bio-functions. Purpose This study was designed to determine the influence of apigenin on …

Comprehensive gene and pathway analysis of cervical cancer progression

Y Yi, Y Fang, K Wu, Y Liu, W Zhang - Oncology letters, 2020 - spandidos-publications.com
Cervical Cancer is one of the leading causes of cancer-associated mortality in women. The
present study aimed to identify key genes and pathways involved in cervical cancer (CC) …

[HTML][HTML] Key considerations on the development of biodegradable biomaterials for clinical translation of medical devices: With cartilage repair products as an example

L Wang, X Guo, J Chen, Z Zhen, B Cao, W Wan… - Bioactive materials, 2022 - Elsevier
With the interdisciplinary convergence of biology, medicine and materials science, both
research and clinical translation of biomaterials are progressing at a rapid pace. However …

The biphasic role of Hspb1 on ferroptotic cell death in Parkinson's disease

J Meng, J Fang, Y Bao, H Chen, X Hu, Z Wang… - …, 2024 - pmc.ncbi.nlm.nih.gov
Rationale: Ferroptosis-driven loss of dopaminergic neurons plays a pivotal role in the
pathogenesis of Parkinson's disease (PD). In PD patients, Hspb1 is commonly observed at …

Se-rich tea polysaccharide extracted by high hydrostatic pressure attenuated anaphylaxis by improving gut microbiota and metabolic regulation

J Ma, M Zhao, Y Wang, L Lv, L Qin, X Ling, J Sun… - International Journal of …, 2024 - Elsevier
Selenium-rich tea polysaccharides (Se-TPS) were extracted via high hydrostatic pressure
technology with a pressure of 400 MPa (200–500 MPa) for 10 min (3–20 min) at a material …

Non-oxidative torrefaction of biomass to enhance its fuel properties

A Álvarez, D Nogueiro, C Pizarro, M Matos, JL Bueno - Energy, 2018 - Elsevier
Torrefaction upgrades the biomass as an energy source enhancing its poorest
characteristics. Non-oxidative torrefaction of six biomass samples (pine, eucalyptus …

Natural compounds against nonalcoholic fatty liver disease: a review on the involvement of the LKB1/AMPK signaling pathway

N Omidkhoda, S Mahdiani, AW Hayes… - Phytotherapy …, 2023 - Wiley Online Library
Although various therapeutic approaches are used to manage nonalcoholic fatty liver
disease (NAFLD), the best approach to NAFLD management is unclear. NAFLD is a liver …