The metabolic syndrome
Abstract The “metabolic syndrome”(MetS) is a clustering of components that reflect
overnutrition, sedentary lifestyles, and resultant excess adiposity. The MetS includes the …
overnutrition, sedentary lifestyles, and resultant excess adiposity. The MetS includes the …
Rodent models for human polycystic ovary syndrome
KA Walters, CM Allan, DJ Handelsman - Biology of reproduction, 2012 - academic.oup.com
Polycystic ovary syndrome (PCOS) is the most frequent female endocrine disorder, affecting
5%–10% of women, causing infertility due to dysfunctional follicular maturation and …
5%–10% of women, causing infertility due to dysfunctional follicular maturation and …
Epigallocatechin gallate attenuates diet-induced obesity in mice by decreasing energy absorption and increasing fat oxidation
OBJECTIVE: To examine the antiobesity effect of epigallocatechin gallate (EGCG), a green
tea bioactive polyphenol in a mouse model of diet-induced obesity. METHODS: Obesity was …
tea bioactive polyphenol in a mouse model of diet-induced obesity. METHODS: Obesity was …
Adiponectin is a novel humoral vasodilator
G Fésüs, G Dubrovska, K Gorzelniak… - Cardiovascular …, 2007 - academic.oup.com
Objectives Perivascular adipose tissue secretes an adipocyte-derived relaxing factor
(s)(ADRF) that opens Kv channels in rat arteries. Visceral fat accumulation causes adipocyte …
(s)(ADRF) that opens Kv channels in rat arteries. Visceral fat accumulation causes adipocyte …
Endothelial nitric oxide synthase uncoupling and perivascular adipose oxidative stress and inflammation contribute to vascular dysfunction in a rodent model of …
The metabolic syndrome represents a constellation of cardiovascular risk factors that
promote the development of cardiovascular disease. Oxidative stress is a mediator of …
promote the development of cardiovascular disease. Oxidative stress is a mediator of …
The genetic landscape of type 2 diabetes in mice
Inbred mouse strains provide genetic diversity comparable to that of the human population.
Like humans, mice have a wide range of diabetes-related phenotypes. The inbred mouse …
Like humans, mice have a wide range of diabetes-related phenotypes. The inbred mouse …
Evidence-based hormonal, mutational, and endocrine-disrupting chemical-induced zebrafish as an alternative model to study PCOS condition similar to mammalian …
Polycystic ovarian syndrome (PCOS) causes swollen ovaries in women at reproductive age
due to hormonal disorder with small cysts on the outer edges. The cause of the disorder is …
due to hormonal disorder with small cysts on the outer edges. The cause of the disorder is …
Tbc1d1 mutation in lean mouse strain confers leanness and protects from diet-induced obesity
A Chadt, K Leicht, A Deshmukh, LQ Jiang… - Nature …, 2008 - nature.com
We previously identified Nob1 as a quantitative trait locus for high-fat diet–induced obesity
and diabetes in genome-wide scans of outcross populations of obese and lean mouse …
and diabetes in genome-wide scans of outcross populations of obese and lean mouse …
Adaptative nitric oxide overproduction in perivascular adipose tissue during early diet-induced obesity
M Gil-Ortega, P Stucchi, R Guzman-Ruiz, V Cano… - …, 2010 - academic.oup.com
Perivascular adipose tissue (PVAT) plays a paracrine role in regulating vascular tone. We
hypothesize that PVAT undergoes adaptative mechanisms during initial steps of diet …
hypothesize that PVAT undergoes adaptative mechanisms during initial steps of diet …
Up to date with human thyroglobulin
SA Van de Graaf, C Ris-Stalpers… - Journal of …, 2001 - joe.bioscientifica.com
The superior ovarian nerve (SON) arrives at the ovary through the suspensory ligament and
innervates mainly the ovarian stroma. Most neurones from which the SON fibres originate …
innervates mainly the ovarian stroma. Most neurones from which the SON fibres originate …