Immunology of acute and chronic wound healing

K Raziyeva, Y Kim, Z Zharkinbekov, K Kassymbek… - Biomolecules, 2021‏ - mdpi.com
Skin wounds greatly affect the global healthcare system, creating a substantial burden on
the economy and society. Moreover, the situation is exacerbated by low healing rates, which …

Advances of hydrogel dressings in diabetic wounds

H Wang, Z Xu, M Zhao, G Liu, J Wu - Biomaterials science, 2021‏ - pubs.rsc.org
Currently, the treatment and care of diabetic wounds, which generally possess the
characteristics of a high amputation rate, high recurrence rate and high mortality, has …

Snail-inspired AFG/GelMA hydrogel accelerates diabetic wound healing via inflammatory cytokines suppression and macrophage polarization

Z Zhou, T Deng, M Tao, L Lin, L Sun, X Song, D Gao… - Biomaterials, 2023‏ - Elsevier
Diabetic foot ulcers (DFUs) are a severe and rapidly growing diabetic complication, but
treating DFUs remains a challenge for the existing therapies are expensive and highly non …

[HTML][HTML] Modulating the immune system towards a functional chronic wound healing: A biomaterials and Nanomedicine perspective

K Las Heras, I Garcia-Orue, F Rancan, M Igartua… - Advanced Drug Delivery …, 2024‏ - Elsevier
Chronic non-healing wounds persist as a substantial burden for healthcare systems,
influenced by factors such as aging, diabetes, and obesity. In contrast to the traditionally pro …

The emerging roles of neutrophil extracellular traps in wound healing

S Zhu, Y Yu, Y Ren, L Xu, H Wang, X Ling, L **… - Cell death & …, 2021‏ - nature.com
Delayed wound healing causes problems for many patients both physically and
psychologically, contributing to pain, economic burden, loss of function, and even …

Ionic liquid functionalized non-releasing antibacterial hydrogel dressing coupled with electrical stimulation for the promotion of diabetic wound healing

P Liu, K **, W Wong, Y Wang, T Liang, M He… - Chemical Engineering …, 2021‏ - Elsevier
Chronic wounds are more difficult to be cured than the general wounds, particularly for the
wounds of diabetic patients. It also increases the risk of bacterial infections and may cause …

[HTML][HTML] Ionic liquid-based non-releasing antibacterial, anti-inflammatory, high-transparency hydrogel coupled with electrical stimulation for infected diabetic wound …

B Liu, R Fu, Z Duan, C Zhu, J Deng, D Fan - Composites Part B …, 2022‏ - Elsevier
Bacterial colonization, prolonged inflammatory phase, angiogenesis difficulties, collagen
deposition deficiency, and other serious complications can impede the infected wound …

Disulfiram accelerates diabetic foot ulcer healing by blocking NET formation via suppressing the NLRP3/Caspase-1/GSDMD pathway

S Yang, Y Feng, L Chen, Z Wang, J Chen, Q Ni… - Translational …, 2023‏ - Elsevier
Diabetic foot ulcer (DFU) is among the most frequent complications of diabetes and is
associated with significant morbidity and mortality. Excessive neutrophil extracellular traps …

Biomaterial-based mechanical regulation facilitates scarless wound healing with functional skin appendage regeneration

YY Li, SF Ji, XB Fu, YF Jiang, XY Sun - Military Medical Research, 2024‏ - Springer
Scar formation resulting from burns or severe trauma can significantly compromise the
structural integrity of skin and lead to permanent loss of skin appendages, ultimately …

Neutrophil extracellular traps delay diabetic wound healing by inducing endothelial-to-mesenchymal transition via the hippo pathway

S Yang, SS Wang, L Chen, Z Wang… - International …, 2023‏ - pmc.ncbi.nlm.nih.gov
Diabetic foot ulcers (DFUs) are among the most frequent complications of diabetes with
significant morbidity and mortality. Diabetes can trigger neutrophils to undergo histone …