Hypolipidemic activity of phytochemical combinations: A mechanistic review of preclinical and clinical studies

H Nechchadi, Y Nadir, K Benhssaine, C Alem… - Food Chemistry, 2024 - Elsevier
Hyperlipidemia, a condition characterized by elevated levels of lipids in the blood, poses a
significant risk factor for various health disorders, notably cardiovascular diseases …

Exploring the mechanism of flavonoids modification by dimerization strategies and their potential to enhance biological activity

P Zou, P Otero, JC Mejuto, J Simal-Gandara, J **ao… - Food Chemistry, 2024 - Elsevier
Flavonoid dimers are being focused due to their particular structure that links two units
through Csingle bondC or COC bonds. This paper provides a comprehensive and …

Phytomedicine for neurodegenerative diseases: The road ahead

D Madhubala, A Patra, MR Khan… - Phytotherapy …, 2024 - Wiley Online Library
Neurodegenerative disorders (NDs) are among the most common causes of death across
the globe. NDs are characterized by progressive damage to CNS neurons, leading to …

Evaluating anti-inflammatory and anti-oxidative potentialities of the chloroform fraction of Asparagus racemosus roots against cisplatin induced acute kidney injury

S Jana, P Mitra, T Panchali, A Khatun, TK Das… - Journal of …, 2025 - Elsevier
Ethnopharmacological relevance Acute kidney injury (AKI), a global public health concern
that increases the risk of death, end-stage renal disease, and prolonged hospital …

Maximizing the Recovery of Phenolic Antioxidants from Wild Strawberry (Fragaria vesca) Leaves Using Microwave-Assisted Extraction and Accelerated Solvent …

P Terpinc, E Dobroslavić, IE Garofulić, M Repajić… - Processes, 2023 - mdpi.com
Due to the presence of diverse phenolic classes in wild strawberry (Fragaria vesca L.)
leaves, there is an ever-growing effort to find new, efficient methods for their recovery and …

Apigenin's Health Benefits in Kidney Disease: Pharmacological Insights and Future Perspectives

J Wu, W Dai, K Li, X Ding, H Gao… - Food Reviews …, 2025 - Taylor & Francis
The incidence of kidney diseases is increasing globally, posing a serious threat to human
health. Studies have shown that apigenin, a natural dietary flavonoid with multiple …

Apigenin: a natural molecule at the intersection of sleep and aging

DJ Kramer, AA Johnson - Frontiers in Nutrition, 2024 - frontiersin.org
NAD+, a pivotal coenzyme central to metabolism, exhibits a characteristic decline with age.
In mice, NAD+ levels can be elevated via treatment with apigenin, a natural flavonoid that …

[HTML][HTML] Ultrasound-assisted metabolite detection in different extraction processes of Bletilla striata and bitter metabolite detection

J Zhou, Y Feng, W Zhou, M Zhang, F Liu, J Mao… - Ultrasonics …, 2025 - Elsevier
Bletilla striata, a medicinal orchidaceous plant, is recognized for its significant
pharmacological value. However, the lack of comparative metabolomic data across different …

Examining the combined benefits of photobiomodulation and apigenin for the treatment of asthenozoospermia: An innovative therapeutic strategy

Z Al-Timimi - Photochemical & Photobiological Sciences, 2024 - Springer
Individuals suffering from asthenospermia, an infertility disorder, have reduced sperm
motility. This study's goal was to identify the impacts of diverse photobiomodulation …

Sludge-derived biostimulants promote glycosylation of tricin and luteolin in the flavone and flavonol biosynthesis to enhance anti-inflammatory activities of rice

X Yuan, Y Hua, S Chen, Q Song, X Li, Y Zhang… - Environmental …, 2024 - Elsevier
Alkaline thermal hydrolysis of sewage sludge produces nutrients and biostimulants that
enhance plant growth, attracting considerable interest in agriculture. However, the metabolic …