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Genistein: an integrative overview of its mode of action, pharmacological properties, and health benefits
Genistein is an isoflavone first isolated from the brooming plant Dyer's Genista tinctoria L.
and is widely distributed in the Fabaceae family. As an isoflavone, mammalian genistein …
and is widely distributed in the Fabaceae family. As an isoflavone, mammalian genistein …
Nuclear factor-kappa B and its role in inflammatory lung disease
Nuclear factor-kappa B, involved in inflammation, host immune response, cell adhesion,
growth signals, cell proliferation, cell differentiation, and apoptosis defense, is a dimeric …
growth signals, cell proliferation, cell differentiation, and apoptosis defense, is a dimeric …
Wogonin and its analogs for the prevention and treatment of cancer: A systematic review
The medicinal plant Scutellaria baicalensis, commonly known as Chinese skullcap or
Huang‐Qin, has been used as a traditional medicine for several thousand years. The roots …
Huang‐Qin, has been used as a traditional medicine for several thousand years. The roots …
Genistein: a potent anti-breast cancer agent
Genistein is an isoflavonoid present in high quantities in soybeans. Possessing a wide
range of bioactives, it is being studied extensively for its tumoricidal effects. Investigations …
range of bioactives, it is being studied extensively for its tumoricidal effects. Investigations …
Antioxidant and anti-inflammation effects of dietary phytochemicals: The Nrf2/NF-κB signalling pathway and upstream factors of Nrf2
S Wu, X Liao, Z Zhu, R Huang, M Chen, A Huang… - Phytochemistry, 2022 - Elsevier
Oxidative stress (OS) is created by an imbalance between reactive oxygen species and
antioxidant levels. OS promotes inflammation and is associated with many diseases, such …
antioxidant levels. OS promotes inflammation and is associated with many diseases, such …
Molecular pathways of genistein activity in breast cancer cells
The most common malignancy in women is breast cancer. During the development of
cancer, oncogenic transcription factors facilitate the overproduction of inflammatory …
cancer, oncogenic transcription factors facilitate the overproduction of inflammatory …
COVID-19, cytokines, inflammation, and spices: How are they related?
Background Cytokine storm is the exaggerated immune response often observed in viral
infections. It is also intimately linked with the progression of COVID-19 disease as well as …
infections. It is also intimately linked with the progression of COVID-19 disease as well as …
Diosgenin, a steroidal saponin, and its analogs: Effective therapies against different chronic diseases
Background Chronic diseases are a major cause of mortality worldwide, and despite the
recent development in treatment modalities, synthetic drugs have continued to show toxic …
recent development in treatment modalities, synthetic drugs have continued to show toxic …
The role of bioactive compounds in natural products extracted from plants in cancer treatment and their mechanisms related to anticancer effects
M Yuan, G Zhang, W Bai, X Han, C Li… - Oxidative Medicine and …, 2022 - Wiley Online Library
Cancer is one of the greatest causes of death worldwide. With the development of surgery,
radiotherapy, and medical agents, the outcomes of cancer patients have greatly improved …
radiotherapy, and medical agents, the outcomes of cancer patients have greatly improved …
Blueberries and their bioactives in the modulation of oxidative stress, inflammation and cardio/vascular function markers: A systematic review of human intervention …
Blueberries represent a rich source of (poly) phenols and other bioactive compounds.
Numerous in vitro and animal model studies documented the potential health-promoting …
Numerous in vitro and animal model studies documented the potential health-promoting …