Next generation sequencing: an application in forensic sciences?

MJ Alvarez-Cubero, M Saiz… - Annals of human …, 2017 - Taylor & Francis
Context: Over the last few decades, advances in sequencing have improved greatly. One of
the most important achievements of Next Generation Sequencing (NGS) is to produce …

[KSIĄŻKA][B] Forensic biology: identification and DNA analysis of biological evidence

R Li - 2008 - taylorfrancis.com
Designed as an accessible introduction to basic scientific principles and their application in
professional practice, Forensic Biology provides a concise overview of the field. Focusing …

Mitochondrial DNA analysis in population isolates: challenges and implications for human identification

JR Connell, RA Lea, LM Haupt, LR Griffiths - Current Molecular Biology …, 2024 - Springer
Abstract Purpose of Review Mitochondrial DNA (mtDNA) plays an essential role in forensic
science, aiding in human identification especially when dealing with degraded DNA …

[HTML][HTML] Evaluation of next generation mtGenome sequencing using the Ion Torrent Personal Genome Machine (PGM)

W Parson, C Strobl, G Huber, B Zimmermann… - Forensic Science …, 2013 - Elsevier
Insights into the human mitochondrial phylogeny have been primarily achieved by
sequencing full mitochondrial genomes (mtGenomes). In forensic genetics (partial) …

DNA capture and next-generation sequencing can recover whole mitochondrial genomes from highly degraded samples for human identification

JEL Templeton, PM Brotherton, B Llamas… - Investigative …, 2013 - Springer
Abstract Background Mitochondrial DNA (mtDNA) ty** can be a useful aid for identifying
people from compromised samples when nuclear DNA is too damaged, degraded or below …

Massively parallel sequencing of complete mitochondrial genomes from hair shaft samples

W Parson, G Huber, L Moreno, MB Madel… - Forensic Science …, 2015 - Elsevier
Though shed hairs are one of the most commonly encountered evidence types, they are
among the most limited in terms of DNA quantity and quality. As a result, DNA testing has …

[PDF][PDF] Second generation sequencing allows for mtDNA mixture deconvolution and high resolution detection of heteroplasmy

MM Holland, MR McQuillan, KA O'Hanlon - Croatian medical journal, 2011 - hrcak.srce.hr
Aim To use parallel array pyrosequencing to deconvolute mixtures of mitochondrial DNA
(mtDNA) sequence and provide high resolution analysis of mtDNA heteroplasmy. Methods …

[HTML][HTML] Full mtGenome reference data: Development and characterization of 588 forensic-quality haplotypes representing three US populations

RS Just, MK Scheible, SA Fast… - Forensic Science …, 2015 - Elsevier
Though investigations into the use of massively parallel sequencing technologies for the
generation of complete mitochondrial genome (mtGenome) profiles from difficult forensic …

DIP–STR: highly sensitive markers for the analysis of unbalanced genomic mixtures

V Castella, J Gervaix, D Hall - Human Mutation, 2013 - Wiley Online Library
Samples containing highly unbalanced DNA mixtures from two individuals commonly occur
both in forensic mixed stains and in peripheral blood DNA microchimerism induced by …

Current next generation sequencing technology may not meet forensic standards

HJ Bandelt, A Salas - Forensic Science International: Genetics, 2012 - Elsevier
In a Nature paper of 2010, the concern was raised that intra-individual mtDNA variation may
be more pronounced than previously believed, in that heteroplasmies are common and vary …