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Next generation sequencing: an application in forensic sciences?
Context: Over the last few decades, advances in sequencing have improved greatly. One of
the most important achievements of Next Generation Sequencing (NGS) is to produce …
the most important achievements of Next Generation Sequencing (NGS) is to produce …
[KSIĄŻKA][B] Forensic biology: identification and DNA analysis of biological evidence
R Li - 2008 - taylorfrancis.com
Designed as an accessible introduction to basic scientific principles and their application in
professional practice, Forensic Biology provides a concise overview of the field. Focusing …
professional practice, Forensic Biology provides a concise overview of the field. Focusing …
Mitochondrial DNA analysis in population isolates: challenges and implications for human identification
Abstract Purpose of Review Mitochondrial DNA (mtDNA) plays an essential role in forensic
science, aiding in human identification especially when dealing with degraded DNA …
science, aiding in human identification especially when dealing with degraded DNA …
[HTML][HTML] Evaluation of next generation mtGenome sequencing using the Ion Torrent Personal Genome Machine (PGM)
W Parson, C Strobl, G Huber, B Zimmermann… - Forensic Science …, 2013 - Elsevier
Insights into the human mitochondrial phylogeny have been primarily achieved by
sequencing full mitochondrial genomes (mtGenomes). In forensic genetics (partial) …
sequencing full mitochondrial genomes (mtGenomes). In forensic genetics (partial) …
DNA capture and next-generation sequencing can recover whole mitochondrial genomes from highly degraded samples for human identification
Abstract Background Mitochondrial DNA (mtDNA) ty** can be a useful aid for identifying
people from compromised samples when nuclear DNA is too damaged, degraded or below …
people from compromised samples when nuclear DNA is too damaged, degraded or below …
Massively parallel sequencing of complete mitochondrial genomes from hair shaft samples
W Parson, G Huber, L Moreno, MB Madel… - Forensic Science …, 2015 - Elsevier
Though shed hairs are one of the most commonly encountered evidence types, they are
among the most limited in terms of DNA quantity and quality. As a result, DNA testing has …
among the most limited in terms of DNA quantity and quality. As a result, DNA testing has …
[PDF][PDF] Second generation sequencing allows for mtDNA mixture deconvolution and high resolution detection of heteroplasmy
MM Holland, MR McQuillan, KA O'Hanlon - Croatian medical journal, 2011 - hrcak.srce.hr
Aim To use parallel array pyrosequencing to deconvolute mixtures of mitochondrial DNA
(mtDNA) sequence and provide high resolution analysis of mtDNA heteroplasmy. Methods …
(mtDNA) sequence and provide high resolution analysis of mtDNA heteroplasmy. Methods …
[HTML][HTML] Full mtGenome reference data: Development and characterization of 588 forensic-quality haplotypes representing three US populations
RS Just, MK Scheible, SA Fast… - Forensic Science …, 2015 - Elsevier
Though investigations into the use of massively parallel sequencing technologies for the
generation of complete mitochondrial genome (mtGenome) profiles from difficult forensic …
generation of complete mitochondrial genome (mtGenome) profiles from difficult forensic …
DIP–STR: highly sensitive markers for the analysis of unbalanced genomic mixtures
V Castella, J Gervaix, D Hall - Human Mutation, 2013 - Wiley Online Library
Samples containing highly unbalanced DNA mixtures from two individuals commonly occur
both in forensic mixed stains and in peripheral blood DNA microchimerism induced by …
both in forensic mixed stains and in peripheral blood DNA microchimerism induced by …
Current next generation sequencing technology may not meet forensic standards
HJ Bandelt, A Salas - Forensic Science International: Genetics, 2012 - Elsevier
In a Nature paper of 2010, the concern was raised that intra-individual mtDNA variation may
be more pronounced than previously believed, in that heteroplasmies are common and vary …
be more pronounced than previously believed, in that heteroplasmies are common and vary …