[HTML][HTML] Endoplasmic reticulum associated protein degradation: a chaperone assisted journey to hell

A Stolz, DH Wolf - Biochimica et Biophysica Acta (BBA)-Molecular Cell …, 2010 - Elsevier
Recognition and elimination of misfolded proteins are essential cellular processes. More
than thirty percent of the cellular proteins are proteins of the secretory pathway. They fold in …

Multiple cytosolic and transmembrane determinants are required for the trafficking of SCAMP1 via an ER–Golgi–TGN–PM pathway

Y Cai, T Jia, SK Lam, Y Ding, C Gao… - The Plant …, 2011 - Wiley Online Library
How polytopic plasma membrane (PM) proteins reach their destination in plant cells remains
elusive. Using transgenic tobacco BY‐2 cells, we previously showed that the rice secretory …

Detection of nonstructural protein 6 in murine coronavirus-infected cells and analysis of the transmembrane topology by using bioinformatics and molecular …

S Baliji, SA Cammer, B Sobral, SC Baker - Journal of virology, 2009 - journals.asm.org
Coronaviruses encode large replicase polyproteins which are proteolytically processed by
viral proteases to generate mature nonstructural proteins (nsps) that form the viral replication …

Saccharomyces cerevisiae Grx6 and Grx7 Are Monothiol Glutaredoxins Associated with the Early Secretory Pathway

A Izquierdo, C Casas, U Mühlenhoff, CH Lillig… - Eukaryotic …, 2008 - journals.asm.org
ABSTRACT Saccharomyces cerevisiae Grx6 and Grx7 are two monothiol glutaredoxins
whose active-site sequences (CSYS and CPYS, respectively) are reminiscent of the CPYC …

A “poly-matter network” conception of biological inheritance

GA Müller, TD Müller - Genetica, 2024 - Springer
Here we intend to shift the “DNA-and information-centric” conception of biological
inheritance, with the accompanying exclusion of any non-DNA matter, to a “poly-matter …

The essential endoplasmic reticulum chaperone Rot1 is required for protein N-and O-glycosylation in yeast

M Pasikowska, G Palamarczyk, L Lehle - Glycobiology, 2012 - academic.oup.com
Rot1 is an essential yeast protein originally shown to be implicated in such diverse
processes such as β-1, 6-glucan synthesis, actin cytoskeleton dynamics or lysis of …

A transmembrane serine residue in the Rot1 protein is essential for yeast cell viability

CA Martinez-Garay, MA Juanes, JC Igual… - Biochemical …, 2014 - portlandpress.com
Polar residues are present in TM (transmembrane) helices and may influence the folding or
association of membrane proteins. In the present study, we use an in vivo approach to …

Targeting and membrane insertion into the endoplasmic reticulum membrane of Saccharomyces cerevisiae essential protein Rot1

MA Juanes, CA Martínez-Garay, JC Igual… - FEMS yeast …, 2010 - academic.oup.com
Rot1 is an essential yeast protein that has been related to cell wall biosynthesis, actin
cytoskeleton dynamics and protein folding. Rot1 is an N-glycosylated protein anchored to …

[PDF][PDF] Rot1, an essential yeast protein, is degraded through the ER-associated protein degradation system (ERAD) M. Angeles Juanes1, 2✉, Carlos A. Martínez …

B i Biomedicina - Journal of Postdoctoral Research November, 2017 - postdocjournal.com
S. cerevisiae ROT1 is an essential gene which has been related to cell wall biosynthesis,
the actin cytoskeleton and protein folding. Rot1 protein is primarily located at the …

Analysis of Membrane Protein Topology in the Plant Secretory Pathway

J Guo, Y Miao, Y Cai - Plant Protein Secretion: Methods and Protocols, 2017 - Springer
Topology of membrane proteins provides important information for the understanding of
protein function and intermolecular associations. Integrate membrane proteins are generally …