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Regulation of peptidoglycan synthesis and remodelling
Bacteria surround their cell membrane with a net-like peptidoglycan layer, called sacculus,
to protect the cell from bursting and maintain its cell shape. Sacculus growth during …
to protect the cell from bursting and maintain its cell shape. Sacculus growth during …
Peptidoglycan NlpC/P60 peptidases in bacterial physiology and host interactions
The bacterial cell wall is composed of a highly crosslinked matrix of glycopeptide polymers
known as peptidoglycan that dictates bacterial cell morphology and protects against …
known as peptidoglycan that dictates bacterial cell morphology and protects against …
Mechanistic insights into the regulation of cell wall hydrolysis by FtsEX and EnvC at the bacterial division site
X Xu, J Li, WZ Chua, MA Pages, J Shi… - Proceedings of the …, 2023 - pnas.org
The peptidoglycan (PG) cell wall produced by the bacterial division machinery is initially
shared between the daughters and must be split to promote cell separation and complete …
shared between the daughters and must be split to promote cell separation and complete …
Intrinsically disordered protein regions are required for cell wall homeostasis in Bacillus subtilis
Intrinsically disordered protein regions (IDRs) have been implicated in diverse nuclear and
cytoplasmic functions in eukaryotes, but their roles in bacteria are less clear. Here, we report …
cytoplasmic functions in eukaryotes, but their roles in bacteria are less clear. Here, we report …
Homeostatic control of cell wall hydrolysis by the WalRK two-component signaling pathway in Bacillus subtilis
Bacterial cells are encased in a peptidoglycan (PG) exoskeleton that protects them from
osmotic lysis and specifies their distinct shapes. Cell wall hydrolases are required to enlarge …
osmotic lysis and specifies their distinct shapes. Cell wall hydrolases are required to enlarge …
Regulation of the cell division hydrolase RipC by the FtsEX system in Mycobacterium tuberculosis
The FtsEX complex regulates, directly or via a protein mediator depending on bacterial
genera, peptidoglycan degradation for cell division. In mycobacteria and Gram-positive …
genera, peptidoglycan degradation for cell division. In mycobacteria and Gram-positive …
Insights into bacterial cell division from a structure of EnvC bound to the FtsX periplasmic domain
J Cook, TC Baverstock, MBL McAndrew… - Proceedings of the …, 2020 - pnas.org
FtsEX is a bacterial ABC transporter that regulates the activity of periplasmic peptidoglycan
amidases via its interaction with the murein hydrolase activator, EnvC. In Escherichia coli …
amidases via its interaction with the murein hydrolase activator, EnvC. In Escherichia coli …
The role of ATP-binding cassette transporters in bacterial phytopathogenesis
Bacteria use selective membrane transporting strategies to support cell survival in different
environments. Of the membrane transport systems, ATP-binding cassette (ABC) …
environments. Of the membrane transport systems, ATP-binding cassette (ABC) …
Not Just Transporters: Alternative Functions of ABC Transporters in Bacillus subtilis and Listeria monocytogenes
J Rismondo, LM Schulz - Microorganisms, 2021 - mdpi.com
ATP-binding cassette (ABC) transporters are usually involved in the translocation of their
cognate substrates, which is driven by ATP hydrolysis. Typically, these transporters are …
cognate substrates, which is driven by ATP hydrolysis. Typically, these transporters are …
Identification of new components of the RipC-FtsEX cell separation pathway of Corynebacterineae
HC Lim, JW Sher, FP Rodriguez-Rivera… - PLoS …, 2019 - journals.plos.org
Several important human pathogens are represented in the Corynebacterineae suborder,
including Mycobacterium tuberculosis and Corynebacterium diphtheriae. These bacteria are …
including Mycobacterium tuberculosis and Corynebacterium diphtheriae. These bacteria are …