Synthesis, bioapplications, and toxicity evaluation of chitosan-based nanoparticles

BR Rizeq, NN Younes, K Rasool… - International journal of …, 2019 - mdpi.com
The development of advanced nanomaterials and technologies is essential in biomedical
engineering to improve the quality of life. Chitosan-based nanomaterials are on the forefront …

Nano-immunotherapy: overcoming delivery challenge of immune checkpoint therapy

SH Kiaie, H Salehi-Shadkami, MJ Sanaei… - Journal of …, 2023 - Springer
Immune checkpoint (ICP) molecules expressed on tumor cells can suppress immune
responses against tumors. ICP therapy promotes anti-tumor immune responses by targeting …

Delivery of MicroRNAs by Chitosan Nanoparticles to Functionally Alter Macrophage Cholesterol Efflux in Vitro and in Vivo

MA Nguyen, H Wyatt, L Susser, M Geoffrion… - ACS …, 2019 - ACS Publications
The prevention and treatment of cardiovascular diseases (CVD) has largely focused on
lowering circulating LDL cholesterol, yet a significant burden of atherosclerotic disease …

Multifaceted applications of chitosan in cancer drug delivery and therapy

A Babu, R Ramesh - Marine drugs, 2017 - mdpi.com
Chitosan is a versatile polysaccharide of biological origin. Due to the biocompatible and
biodegradable nature of chitosan, it is intensively utilized in biomedical applications in …

Chitosan nanocarriers for non-coding RNA therapeutics: A review

S Karthik, S Mohan, I Magesh, A Bharathy… - International Journal of …, 2024 - Elsevier
Abstract Non-coding RNA (ncRNA)-based therapies entail delivering ncRNAs to cells to
regulate gene expression and produce proteins that combat infections, cancer, neurological …

Chitosan nanoparticles for oral photothermally enhanced photodynamic therapy of colon cancer

G Chen, Y Zhao, Y Xu, C Zhu, T Liu, K Wang - International Journal of …, 2020 - Elsevier
Phototherapy exerts its anticancer effects by converting laser radiation energy into
hyperthermia or reactive singlet oxygen (1 O 2). In this study, we developed chitosan …

[HTML][HTML] Layer by layer assembled chitosan-coated gold nanoparticles for enhanced siRNA delivery and silencing

E Shaabani, M Sharifiaghdam… - International journal of …, 2021 - mdpi.com
Delivery of small interfering RNA (siRNA) provides one of the most powerful strategies for
downregulation of therapeutic targets. Despite the widely explored capabilities of this …

Synthesis and assembly of click‐nucleic‐acid‐containing PEG–PLGA nanoparticles for DNA delivery

A Harguindey, DW Domaille, BD Fairbanks… - Advanced …, 2017 - Wiley Online Library
Co‐delivery of both chemotherapy drugs and siRNA from a single delivery vehicle can have
a significant impact on cancer therapy due to the potential for overcoming issues such as …

Antibacterial, anti-biofilm and pro-migratory effects of double layered hydrogels packaged with lactoferrin-DsiRNA-silver nanoparticles for chronic wound therapy

MAM Fathil, H Katas - Pharmaceutics, 2023 - mdpi.com
Antimicrobial resistance and biofilm formation in diabetic foot infections worsened during the
COVID-19 pandemic, resulting in more severe infections and increased amputations …

Chitosan applications in studying and managing osteosarcoma

PM Dana, J Hallajzadeh, Z Asemi… - International journal of …, 2021 - Elsevier
Osteosarcoma has a high prevalence among children and adolescents. Common treatments
of this disease are not promising enough. Molecular processes involved in the pathogenesis …