In the central nervous system (CNS), myelin sheaths around axons are formed by glial cells
named oligodendrocytes (OLs). In turn, OLs are generated by oligodendrocyte precursor …

Glial cells, consisting of astrocytes, oligodendrocyte lineage cells, and microglia, account
for> 50% of the total number of cells in the mammalian brain. They play key roles in the …

During myelination, individual oligodendrocytes initially over-produce short myelin sheaths,
which are either retracted or stabilized. By live-imaging oligodendrocyte Ca2+ activity in …

Neuronal activity is a potent extrinsic regulator of oligodendrocyte generation and central
nervous system myelination. Clinically, repetitive transcranial magnetic stimulation (rTMS) is …

Citrullination, the deimination of peptidylarginine residues into peptidylcitrulline, has been
implicated in the etiology of several diseases. In multiple sclerosis, citrullination is thought to …

Multiple sclerosis (MS) is the most demyelinating disease of the central nervous system
(CNS) characterized by neuroinflammation. Oligodendrocyte progenitor cells (OPCs) are …

In the brain, neurons establish bona fide synapses onto oligodendrocyte precursor cells
(OPCs), but the function of these neuron‐glia synapses remains unresolved. A leading …

Preterm birth is associated with poor long-term neurodevelopmental and behavioral
outcomes, even in the absence of obvious brain injury at the time of birth. In particular …

Throughout life, oligodendrocyte progenitor cells (OPCs) proliferate and differentiate into
myelinating oligodendrocytes. OPCs express cell surface receptors and channels that allow …

Abstract Calcium (Ca 2+) is an essential component in intracellular signaling of brain cells,
and its control mechanisms are of great interest in biological systems. Ca 2+ can signal …