Diagnosis and management of bronchopulmonary dysplasia

M Gilfillan, A Bhandari, V Bhandari - Bmj, 2021 - bmj.com
Bronchopulmonary dysplasia (BPD) is the most common chronic lung disease in infants and
is associated with increased mortality, respiratory morbidity, neurodevelopmental …

Recent advances in our understanding of the mechanisms of lung alveolarization and bronchopulmonary dysplasia

E Lignelli, F Palumbo, D Myti… - American Journal of …, 2019 - journals.physiology.org
Bronchopulmonary dysplasia (BPD) is the most common cause of morbidity and mortality in
preterm infants. A key histopathological feature of BPD is stunted late lung development …

[HTML][HTML] Pathogenesis of bronchopulmonary dysplasia: role of oxidative stress from 'Omics' studies

A Kimble, ME Robbins, M Perez - Antioxidants, 2022 - mdpi.com
Bronchopulmonary dysplasia (BPD) remains the most common respiratory complication of
prematurity as younger and smaller infants are surviving beyond the immediate neonatal …

[HTML][HTML] Emerging role of metabolic reprogramming in hyperoxia-associated neonatal diseases

T Sun, H Yu, D Li, H Zhang, J Fu - Redox Biology, 2023 - Elsevier
Oxygen therapy is common during the neonatal period to improve survival, but it can
increase the risk of oxygen toxicity. Hyperoxia can damage multiple organs and systems in …

Intermittent hypoxemia and bronchopulmonary dysplasia with pulmonary hypertension in preterm infants

SJ Gentle, CP Travers, A Nakhmani, P Indic… - American journal of …, 2023 - atsjournals.org
Rationale: Bedside biomarkers that allow early identification of infants with
bronchopulmonary dysplasia-associated pulmonary hypertension (BPD-PH) are critically …

Recent advances in understanding and management of bronchopulmonary dysplasia

M Sahni, V Bhandari - F1000Research, 2020 - pmc.ncbi.nlm.nih.gov
In the current era, the survival of extremely low-birth-weight infants has increased
considerably because of new advances in technology; however, these infants often develop …

Longitudinal serum metabolomics in extremely premature infants: relationships with gestational age, nutrition, and morbidities

AK Nilsson, A Tebani, D Malmodin… - Frontiers in …, 2022 - frontiersin.org
An increasing number of extremely premature infants survive the neonatal period and
beyond. Little is known about the maturation of the preterm infant's metabolome and its …

Pulmonary phenotypes of bronchopulmonary dysplasia in the preterm infant

M Gilfillan, V Bhandari - Seminars in perinatology, 2023 - Elsevier
Bronchopulmonary dysplasia (BPD) remains the most common complication of premature
birth, imposing a significant and potentially life-long burden on patients and their families …

Identification of new biomarkers of bronchopulmonary dysplasia using metabolomics

F Piersigilli, TKT Lam, P Vernocchi, A Quagliariello… - Metabolomics, 2019 - Springer
Objective To identify new biomarkers of bronchopulmonary dysplasia (BPD) in preterm
neonates. Study design Metabolomic study of prospectively collected tracheal aspirate (TA) …

[HTML][HTML] A multi-omic analysis of birthweight in newborn cord blood reveals new underlying mechanisms related to cholesterol metabolism

R Alfano, M Chadeau-Hyam, A Ghantous… - Metabolism, 2020 - Elsevier
Background Birthweight reflects in utero exposures and later health evolution. Despite
existing studies employing high-dimensional molecular measurements, the understanding …