[HTML][HTML] Next-generation machine learning for biological networks
Machine learning, a collection of data-analytical techniques aimed at building predictive
models from multi-dimensional datasets, is becoming integral to modern biological research …
models from multi-dimensional datasets, is becoming integral to modern biological research …
Metabolic flexibility as an adaptation to energy resources and requirements in health and disease
RL Smith, MR Soeters, RCI Wüst… - Endocrine …, 2018 - academic.oup.com
The ability to efficiently adapt metabolism by substrate sensing, trafficking, storage, and
utilization, dependent on availability and requirement, is known as metabolic flexibility. In …
utilization, dependent on availability and requirement, is known as metabolic flexibility. In …
Endothelial cell metabolism
G Eelen, P de Zeeuw, L Treps, U Harjes… - Physiological …, 2018 - journals.physiology.org
Endothelial cells (ECs) are more than inert blood vessel lining material. Instead, they are
active players in the formation of new blood vessels (angiogenesis) both in health and (life …
active players in the formation of new blood vessels (angiogenesis) both in health and (life …
[HTML][HTML] Biomarkers of nutrition for development—folate review
Abstract The Biomarkers of Nutrition for Development (BOND) project is designed to provide
evidence-based advice to anyone with an interest in the role of nutrition in health …
evidence-based advice to anyone with an interest in the role of nutrition in health …
A community-driven global reconstruction of human metabolism
Multiple models of human metabolism have been reconstructed, but each represents only a
subset of our knowledge. Here we describe Recon 2, a community-driven, consensus' …
subset of our knowledge. Here we describe Recon 2, a community-driven, consensus' …
[HTML][HTML] Artificial intelligence and early detection of pancreatic cancer: 2020 summative review
Despite considerable research efforts, pancreatic cancer is associated with a dire prognosis
and a 5-year survival rate of only 10%. Early symptoms of the disease are mostly …
and a 5-year survival rate of only 10%. Early symptoms of the disease are mostly …
Genome-scale models in human metabologenomics
Metabologenomics integrates metabolomics with other omics data types to comprehensively
study the genetic and environmental factors that influence metabolism. These multi-omics …
study the genetic and environmental factors that influence metabolism. These multi-omics …
ChemSpot: a hybrid system for chemical named entity recognition
Motivation: The accurate identification of chemicals in text is important for many applications,
including computer-assisted reconstruction of metabolic networks or retrieval of information …
including computer-assisted reconstruction of metabolic networks or retrieval of information …
Reconstruction of genome-scale metabolic models for 126 human tissues using mCADRE
Background Human tissues perform diverse metabolic functions. Map** out these tissue-
specific functions in genome-scale models will advance our understanding of the metabolic …
specific functions in genome-scale models will advance our understanding of the metabolic …
Using networks to measure similarity between genes: association index selection
Biological networks can be used to functionally annotate genes on the basis of interaction-
profile similarities. Metrics known as association indices can be used to quantify interaction …
profile similarities. Metrics known as association indices can be used to quantify interaction …