Oestradiol as a neuromodulator of learning and memory
Although hormones such as glucocorticoids have been broadly accepted in recent decades
as general neuromodulators of memory processes, sex steroid hormones such as the potent …
as general neuromodulators of memory processes, sex steroid hormones such as the potent …
A role for estrogen in schizophrenia: clinical and preclinical findings
Gender differences in schizophrenia have been extensively researched and it is being
increasingly accepted that gonadal steroids are strongly attributed to this phenomenon. Of …
increasingly accepted that gonadal steroids are strongly attributed to this phenomenon. Of …
[HTML][HTML] The role of estrogen in brain and cognitive aging
There are 3 common physiological estrogens, of which estradiol (E2) is seen to decline
rapidly over the menopausal transition. This decline in E2 has been associated with a …
rapidly over the menopausal transition. This decline in E2 has been associated with a …
Hippocampal learning, memory, and neurogenesis: Effects of sex and estrogens across the lifespan in adults
This article is part of a Special Issue “Estradiol and Cognition”. There are sex differences in
hippocampus-dependent cognition and neurogenesis suggesting that sex hormones are …
hippocampus-dependent cognition and neurogenesis suggesting that sex hormones are …
Why estrogens matter for behavior and brain health
Abstract The National Institutes of Health (NIH) has required the inclusion of women in
clinical studies since 1993, which has enhanced our understanding of how biological sex …
clinical studies since 1993, which has enhanced our understanding of how biological sex …
17β-Estradiol and agonism of G-protein-coupled estrogen receptor enhance hippocampal memory via different cell-signaling mechanisms
J Kim, JS Szinte, MI Boulware… - Journal of Neuroscience, 2016 - Soc Neuroscience
The ability of 17β-estradiol (E2) to enhance hippocampal object recognition and spatial
memory depends on rapid activation of extracellular signal-regulated kinase (ERK) in the …
memory depends on rapid activation of extracellular signal-regulated kinase (ERK) in the …
[PDF][PDF] PJA1 mediates the effects of astrocytic GPR30 on learning and memory in female mice
X Wang, Y Jiang, B Feng, X Ma… - Journal of Clinical …, 2023 - Am Soc Clin Investig
Hormone replacement therapy (HRT) is not recommended for treating learning and memory
decline in menopausal women because it exerts adverse effects by activating classic …
decline in menopausal women because it exerts adverse effects by activating classic …
GPER1/GPR30 in the brain: crosstalk with classical estrogen receptors and implications for behavior
MM Hadjimarkou, N Vasudevan - The Journal of Steroid Biochemistry and …, 2018 - Elsevier
The GPER1/GPR30 is a membrane estrogen receptor (mER) that binds 17β-estradiol (17β-
E) with high affinity and is thought to play a role in cancer progression and cardiovascular …
E) with high affinity and is thought to play a role in cancer progression and cardiovascular …
Estrogens and cognition: Friends or foes?: An evaluation of the opposing effects of estrogens on learning and memory
DL Korol, SL Pisani - Hormones and behavior, 2015 - Elsevier
This article is part of a Special Issue “Estradiol and cognition”. Estrogens are becoming well
known for their robust enhancement on cognition particularly for learning and memory that …
known for their robust enhancement on cognition particularly for learning and memory that …
Rapid effects of the G-protein coupled oestrogen receptor (GPER) on learning and dorsal hippocampus dendritic spines in female mice
Recently, oestrogen receptors (ERs) have been implicated in rapid learning processes. We
have previously shown that 17β-estradiol, ERα and ERβ agonists can improve learning …
have previously shown that 17β-estradiol, ERα and ERβ agonists can improve learning …