Clinical trials are the essential assessment for safe, reliable, and effective drug
development. Data-related limitations, extensive manual efforts, remote patient monitoring …

Introduction The aim of the present review is to track the evolution of wearable IMUs from
their use in supervised laboratory-and ambulatory-based settings to their application for long …

With disease-modifying drugs on the horizon for degenerative ataxias, ecologically valid,
finely granulated, digital health measures are highly warranted to augment clinical and …

Physical mobility is essential to health, and patients often rate it as a high-priority clinical
outcome. Digital mobility outcomes (DMOs), such as real-world gait speed or step count …

Digital data play an increasingly important role in advancing health research and care.
However, most digital data in healthcare are in an unstructured and often not readily …

The availability of different telemedicine tools for remote consultation, monitoring, and
treatment is increasing. Future research should establish whether telemedicine improves …

Background The development of optimal strategies to treat impaired mobility related to
ageing and chronic disease requires better ways to detect and measure it. Digital health …

To support the successful adoption of digital measures into internal decision making and
evidence generation for medical product development, we present a unified lexicon to aid …

Parkinson's disease (PD) is a multifactorial neurodegenerative disorder with high
prevalence among the elderly, primarily manifested by progressive decline in motor function …

Neurological disorders represent some of the most challenging therapeutic areas for
successful drug approvals. The escalating global burden of death and disability for such …