Epstein Barr virus: development of vaccines and immune cell therapy for EBV-associated diseases

X Cui, CM Snapper - Frontiers in Immunology, 2021 - frontiersin.org
Epstein-Barr virus (EBV) is the first human tumor virus discovered and is strongly implicated
in the etiology of multiple lymphoid and epithelial cancers. Each year EBV associated …

mRNA vaccines: The future of prevention of viral infections?

P Rzymski, A Szuster‐Ciesielska… - Journal of medical …, 2023 - Wiley Online Library
Messenger RNA (mRNA) vaccines against COVID‐19 are the first authorized biological
preparations developed using this platform. During the pandemic, their administration has …

EBV-associated diseases: Current therapeutics and emerging technologies

S Chakravorty, B Afzali, M Kazemian - Frontiers in immunology, 2022 - frontiersin.org
EBV is a prevalent virus, infecting> 90% of the world's population. This is an oncogenic virus
that causes~ 200,000 cancer-related deaths annually. It is, in addition, a significant …

Urgency and necessity of Epstein-Barr virus prophylactic vaccines

L Zhong, C Krummenacher, W Zhang, J Hong, Q Feng… - Npj Vaccines, 2022 - nature.com
Abstract Epstein-Barr virus (EBV), a γ-herpesvirus, is the first identified oncogenic virus,
which establishes permanent infection in humans. EBV causes infectious mononucleosis …

Epstein-Barr virus is present in the brain of most cases of multiple sclerosis and may engage more than just B cells

A Hassani, JR Corboy, S Al-Salam, G Khan - PloS one, 2018 - journals.plos.org
Multiple sclerosis (MS) is a chronic neuroinflammatory condition of the central nervous
system (CNS). It is a major cause of neurological disability in young adults, particularly …

Vaccine development for Epstein-Barr virus

JI Cohen - Human Herpesviruses, 2018 - Springer
Epstein-Barr virus (EBV) is the primary cause of infectious mononucleosis and is associated
with several malignancies, including nasopharyngeal carcinoma, gastric carcinoma …

The potential for EBV vaccines to prevent multiple sclerosis

PA Maple, A Ascherio, JI Cohen, G Cutter… - Frontiers in …, 2022 - frontiersin.org
There is increasing evidence suggesting that Epstein-Barr virus infection is a causative
factor of multiple sclerosis (MS). Epstein-Barr virus (EBV) is a human herpesvirus, Human …

Progress in EBV vaccines

DG Van Zyl, J Mautner, HJ Delecluse - Frontiers in oncology, 2019 - frontiersin.org
The Epstein-Barr virus (EBV) is a ubiquitous pathogen that imparts a significant burden of
disease on the human population. EBV is the primary cause of infectious mononucleosis …

[HTML][HTML] T cell-mediated immunity during Epstein–Barr virus infections in children

M Liu, R Wang, Z **e - Infection, Genetics and Evolution, 2023 - Elsevier
Epstein–Barr virus (EBV) infection is extremely common worldwide, with approximately 90%
of adults testing positive for EBV antibodies. Human are susceptible to EBV infection, and …

The promise of a prophylactic Epstein–Barr virus vaccine

HH Balfour Jr, DO Schmeling, JM Grimm-Geris - Pediatric research, 2020 - nature.com
The worldwide burden of disease due to Epstein–Barr virus (EBV) infection is enormous.
Diseases include endemic Burkitt lymphoma, infectious mononucleosis, cancers after …