[HTML][HTML] Exploration and insights into the cellular internalization and intracellular fate of amphiphilic polymeric nanocarriers

S Mazumdar, D Chitkara, A Mittal - Acta Pharmaceutica Sinica B, 2021 - Elsevier
The beneficial or deleterious effects of nanomedicines emerge from their complex
interactions with intracellular pathways and their subcellular fate. Moreover, the dynamic …

Magnetic nanoparticles: essential factors for sustainable environmental applications

SCN Tang, IMC Lo - Water research, 2013 - Elsevier
In recent years, there has been an increasing use of engineered magnetic nanoparticles for
remediation and water treatments, leading to elevated public concerns. To this end, it is …

Effect of surface properties on nanoparticle–cell interactions

A Verma, F Stellacci - small, 2010 - Wiley Online Library
The interaction of nanomaterials with cells and lipid bilayers is critical in many applications
such as phototherapy, imaging, and drug/gene delivery. These applications require a firm …

Nanoparticle interaction with plasma proteins as it relates to particle biodistribution, biocompatibility and therapeutic efficacy

P Aggarwal, JB Hall, CB McLeland… - Advanced drug delivery …, 2009 - Elsevier
Proteins bind the surfaces of nanoparticles, and biological materials in general, immediately
upon introduction of the materials into a physiological environment. The further biological …

Inorganic nanoparticles engineered to attack bacteria

KP Miller, L Wang, BC Benicewicz… - Chemical Society …, 2015 - pubs.rsc.org
Antibiotics were once the golden bullet to constrain infectious bacteria. However, the rapid
and continuing emergence of antibiotic resistance (AR) among infectious microbial …

Stealth properties to improve therapeutic efficacy of drug nanocarriers

S Salmaso, P Caliceti - Journal of drug delivery, 2013 - Wiley Online Library
Over the last few decades, nanocarriers for drug delivery have emerged as powerful tools
with unquestionable potential to improve the therapeutic efficacy of anticancer drugs. Many …

Assessment of PEG on polymeric particles surface, a key step in drug carrier translation

JM Rabanel, P Hildgen, X Banquy - Journal of controlled release, 2014 - Elsevier
Injectable drug nanocarriers have greatly benefited in their clinical development from the
addition of a superficial hydrophilic corona to improve their cargo pharmacokinetics. The …

Recent advances in PEG–PLA block copolymer nanoparticles

RZ **ao, ZW Zeng, GL Zhou, JJ Wang… - International journal …, 2010 - Taylor & Francis
Due to their small particle size and large and modifiable surface, nanoparticles have unique
advantages compared with other drug carriers. As a research focus in recent years …

Differential plasma protein binding to metal oxide nanoparticles

ZJ Deng, G Mortimer, T Schiller, A Musumeci… - …, 2009 - iopscience.iop.org
Nanoparticles rapidly interact with the proteins present in biological fluids, such as blood.
The proteins that are adsorbed onto the surface potentially dictate the biokinetics of the …

Hypoxic tumor microenvironment: Opportunities to develop targeted therapies

A Patel, S Sant - Biotechnology advances, 2016 - Elsevier
In recent years, there has been great progress in the understanding of tumor biology and its
surrounding microenvironment. Solid tumors create regions with low oxygen levels …