[HTML][HTML] Exploration and insights into the cellular internalization and intracellular fate of amphiphilic polymeric nanocarriers
The beneficial or deleterious effects of nanomedicines emerge from their complex
interactions with intracellular pathways and their subcellular fate. Moreover, the dynamic …
interactions with intracellular pathways and their subcellular fate. Moreover, the dynamic …
Magnetic nanoparticles: essential factors for sustainable environmental applications
SCN Tang, IMC Lo - Water research, 2013 - Elsevier
In recent years, there has been an increasing use of engineered magnetic nanoparticles for
remediation and water treatments, leading to elevated public concerns. To this end, it is …
remediation and water treatments, leading to elevated public concerns. To this end, it is …
Effect of surface properties on nanoparticle–cell interactions
A Verma, F Stellacci - small, 2010 - Wiley Online Library
The interaction of nanomaterials with cells and lipid bilayers is critical in many applications
such as phototherapy, imaging, and drug/gene delivery. These applications require a firm …
such as phototherapy, imaging, and drug/gene delivery. These applications require a firm …
Nanoparticle interaction with plasma proteins as it relates to particle biodistribution, biocompatibility and therapeutic efficacy
P Aggarwal, JB Hall, CB McLeland… - Advanced drug delivery …, 2009 - Elsevier
Proteins bind the surfaces of nanoparticles, and biological materials in general, immediately
upon introduction of the materials into a physiological environment. The further biological …
upon introduction of the materials into a physiological environment. The further biological …
Inorganic nanoparticles engineered to attack bacteria
KP Miller, L Wang, BC Benicewicz… - Chemical Society …, 2015 - pubs.rsc.org
Antibiotics were once the golden bullet to constrain infectious bacteria. However, the rapid
and continuing emergence of antibiotic resistance (AR) among infectious microbial …
and continuing emergence of antibiotic resistance (AR) among infectious microbial …
Stealth properties to improve therapeutic efficacy of drug nanocarriers
S Salmaso, P Caliceti - Journal of drug delivery, 2013 - Wiley Online Library
Over the last few decades, nanocarriers for drug delivery have emerged as powerful tools
with unquestionable potential to improve the therapeutic efficacy of anticancer drugs. Many …
with unquestionable potential to improve the therapeutic efficacy of anticancer drugs. Many …
Assessment of PEG on polymeric particles surface, a key step in drug carrier translation
Injectable drug nanocarriers have greatly benefited in their clinical development from the
addition of a superficial hydrophilic corona to improve their cargo pharmacokinetics. The …
addition of a superficial hydrophilic corona to improve their cargo pharmacokinetics. The …
Recent advances in PEG–PLA block copolymer nanoparticles
RZ **ao, ZW Zeng, GL Zhou, JJ Wang… - International journal …, 2010 - Taylor & Francis
Due to their small particle size and large and modifiable surface, nanoparticles have unique
advantages compared with other drug carriers. As a research focus in recent years …
advantages compared with other drug carriers. As a research focus in recent years …
Differential plasma protein binding to metal oxide nanoparticles
Nanoparticles rapidly interact with the proteins present in biological fluids, such as blood.
The proteins that are adsorbed onto the surface potentially dictate the biokinetics of the …
The proteins that are adsorbed onto the surface potentially dictate the biokinetics of the …
Hypoxic tumor microenvironment: Opportunities to develop targeted therapies
In recent years, there has been great progress in the understanding of tumor biology and its
surrounding microenvironment. Solid tumors create regions with low oxygen levels …
surrounding microenvironment. Solid tumors create regions with low oxygen levels …