Zebrafish as an emerging model for studying complex brain disorders

AV Kalueff, AM Stewart, R Gerlai - Trends in pharmacological sciences, 2014 - cell.com
The zebrafish (Danio rerio) is rapidly becoming a popular model organism in
pharmacogenetics and neuropharmacology. Both larval and adult zebrafish are currently …

Towards a comprehensive catalog of zebrafish behavior 1.0 and beyond

AV Kalueff, M Gebhardt, AM Stewart, JM Cachat… - Zebrafish, 2013 - liebertpub.com
Zebrafish (Danio rerio) are rapidly gaining popularity in translational neuroscience and
behavioral research. Physiological similarity to mammals, ease of genetic manipulations …

Acute toxic effects of polyethylene microplastic on adult zebrafish

CW Mak, KCF Yeung, KM Chan - Ecotoxicology and environmental safety, 2019 - Elsevier
To identify the physical effects, behavioral changes, and gene expression profiles of the
phase 1 detoxification-related gene (cyp 1a) and oogenesis-related gene (vtg 1) induced by …

The develo** utility of zebrafish models of neurological and neuropsychiatric disorders: A critical review

BD Fontana, NJ Mezzomo, AV Kalueff… - Experimental …, 2018 - Elsevier
Zebrafish (Danio rerio) have become a powerful tool in neuroscience research due to their
genetic tractability, molecular/physiological conservation, small body size, ease of …

Zebrafish behavior: opportunities and challenges

MB Orger, GG de Polavieja - Annual review of neuroscience, 2017 - annualreviews.org
A great challenge in neuroscience is understanding how activity in the brain gives rise to
behavior. The zebrafish is an ideal vertebrate model to address this challenge, thanks to the …

Molecular psychiatry of zebrafish

AM Stewart, JFP Ullmann, WHJ Norton, MO Parker… - Molecular …, 2015 - nature.com
Due to their well-characterized neural development and high genetic homology to
mammals, zebrafish (Danio rerio) have emerged as a powerful model organism in the field …

Neural systems that facilitate the representation of social rank

MF Dwortz, JP Curley, KM Tye… - … Transactions of the …, 2022 - royalsocietypublishing.org
Across species, animals organize into social dominance hierarchies that serve to decrease
aggression and facilitate survival of the group. Neuroscientists have adopted several model …

Social conflict resolution regulated by two dorsal habenular subregions in zebrafish

MY Chou, R Amo, M Kinoshita, BW Cherng… - Science, 2016 - science.org
When animals encounter conflict they initiate and escalate aggression to establish and
maintain a social hierarchy. The neural mechanisms by which animals resolve fighting …

Zebrafish models of autism spectrum disorder

DA Meshalkina, MN Kizlyk, EV Kysil, AD Collier… - Experimental …, 2018 - Elsevier
Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder characterized
by motor, social and cognitive deficits that develop early during childhood. The …

Mind the fish: zebrafish as a model in cognitive social neuroscience

RF Oliveira - Frontiers in neural circuits, 2013 - frontiersin.org
Understanding how the brain implements social behavior on one hand, and how social
processes feedback on the brain to promote fine-tuning of behavioral output according to …