[HTML][HTML] Nanopore sequencing technology, bioinformatics and applications
Rapid advances in nanopore technologies for sequencing single long DNA and RNA
molecules have led to substantial improvements in accuracy, read length and throughput …
molecules have led to substantial improvements in accuracy, read length and throughput …
Fundamental biological features of spaceflight: advancing the field to enable deep-space exploration
Research on astronaut health and model organisms have revealed six features of
spaceflight biology that guide our current understanding of fundamental molecular changes …
spaceflight biology that guide our current understanding of fundamental molecular changes …
Accurate detection of m6A RNA modifications in native RNA sequences
The epitranscriptomics field has undergone an enormous expansion in the last few years;
however, a major limitation is the lack of generic methods to map RNA modifications …
however, a major limitation is the lack of generic methods to map RNA modifications …
Towards a genomics-informed, real-time, global pathogen surveillance system
Abstract The recent Ebola and Zika epidemics demonstrate the need for the continuous
surveillance, rapid diagnosis and real-time tracking of emerging infectious diseases. Fast …
surveillance, rapid diagnosis and real-time tracking of emerging infectious diseases. Fast …
Nanopore DNA sequencing and genome assembly on the International Space Station
We evaluated the performance of the MinION DNA sequencer in-flight on the International
Space Station (ISS), and benchmarked its performance off-Earth against the MinION …
Space Station (ISS), and benchmarked its performance off-Earth against the MinION …
Characterization of the total and viable bacterial and fungal communities associated with the International Space Station surfaces
Abstract Background The International Space Station (ISS) is a closed system inhabited by
microorganisms originating from life support systems, cargo, and crew that are exposed to …
microorganisms originating from life support systems, cargo, and crew that are exposed to …
Chiron: translating nanopore raw signal directly into nucleotide sequence using deep learning
Sequencing by translocating DNA fragments through an array of nanopores is a rapidly
maturing technology that offers faster and cheaper sequencing than other approaches …
maturing technology that offers faster and cheaper sequencing than other approaches …
Biological research and self-driving labs in deep space supported by artificial intelligence
Abstract Space biology research aims to understand fundamental spaceflight effects on
organisms, develop foundational knowledge to support deep space exploration and …
organisms, develop foundational knowledge to support deep space exploration and …
Portable nanopore-sequencing technology: Trends in development and applications
P Chen, Z Sun, J Wang, X Liu, Y Bai, J Chen… - Frontiers in …, 2023 - frontiersin.org
Sequencing technology is the most commonly used technology in molecular biology
research and an essential pillar for the development and applications of molecular biology …
research and an essential pillar for the development and applications of molecular biology …
The impact of heterogeneity on single-cell sequencing
The importance of diversity and cellular specialization is clear for many reasons, from
population-level diversification, to improved resiliency to unforeseen stresses, to unique …
population-level diversification, to improved resiliency to unforeseen stresses, to unique …