Idiopathic pulmonary fibrosis (IPF) is a progressive fibrotic lung disease characterised by
worsening respiratory symptoms and physiological impairment. Increasing awareness of the …

The pathogenesis of idiopathic pulmonary fibrosis (IPF) involves a complex interplay of cell
types and signaling pathways. Recurrent alveolar epithelial cell (AEC) injury may occur in …

To explore the biology of lung adenocarcinoma (LUAD) and identify new therapeutic
opportunities, we performed comprehensive proteogenomic characterization of 110 tumors …

Idiopathic pulmonary fibrosis (IPF) is a chronic progressive disease of unknown cause
characterized by relentless scarring of the lung parenchyma leading to reduced quality of life …

Pulmonary fibrosis (PF) is a form of chronic lung disease characterized by pathologic
epithelial remodeling and accumulation of extracellular matrix (ECM). To comprehensively …

Idiopathic pulmonary fibrosis is a prototype of chronic, progressive, and fibrotic lung disease.
Healthy tissue is replaced by altered extracellular matrix and alveolar architecture is …

Activation of TGF-β1 initiates a program of temporary collagen accumulation important to
wound repair in many organs. However, the outcome of temporary extracellular matrix …

Fibrosis can develop in most organs and causes organ failure. The most common type of
lung fibrosis is known as idiopathic pulmonary fibrosis, in which fibrosis starts at the lung …

Parenchymal lung disease is the fourth leading cause of death in the United States; among
the top causes, it continues on the rise. Telomeres and telomerase have historically been …

Idiopathic pulmonary fibrosis (IPF) is a prototype of lethal, chronic, progressive interstitial
lung disease of unknown etiology. Over the past decade, macrophage has been recognized …