Plasmids are key vectors of horizontal gene transfer and essential genetic engineering tools.
They code for genes involved in many aspects of microbial biology, including detoxication …

Figure 1 Screenshot of a session with Clustal X in split-window mode for profile alignment.
Archaeal TFIIB sequences (lower window) are aligned with prealigned eukaryotic TFIIBs …

We present SeaView version 4, a multiplatform program designed to facilitate multiple
alignment and phylogenetic tree building from molecular sequence data through the use of …

We present an expansion of the classification of the family Papillomaviridae, which now
contains 29 genera formed by 189 papillomavirus (PV) types isolated from humans (120 …

Jalview Version 2 is a system for interactive WYSIWYG editing, analysis and annotation of
multiple sequence alignments. Core features include keyboard and mouse-based editing …

CLUSTAL X is a new windows interface for the widely-used progressive multiple sequence
alignment program CLUSTAL W. The new system is easy to use, providing an integrated …

Marburg virus (family Filoviridae) causes sporadic outbreaks of severe hemorrhagic disease
in sub-Saharan Africa. Bats have been implicated as likely natural reservoir hosts based …

We describe here the complete genome sequence (1,111,523 base pairs) of the obligate
intracellular parasite Rickettsia prowazekii, the causative agent of epidemic typhus. This …

Background Development of phylogenetic methods that do not rely on fossils for the study of
evolutionary processes through time have revolutionized the field of evolutionary biology …

Until now the most efficient solution to align nucleotide sequences containing open reading
frames was to use indirect procedures that align amino acid translation before reporting the …