Bioinformatics: from NGS data to biological complexity in variant detection and oncological clinical practice

S Dotolo, R Esposito Abate, C Roma, D Guido… - Biomedicines, 2022 - mdpi.com
The use of next-generation sequencing (NGS) techniques for variant detection has become
increasingly important in clinical research and in clinical practice in oncology. Many cancer …

Identification of a novel gene signature predicting response to first-line chemotherapy in BRCA wild-type high-grade serous ovarian cancer patients

M Buttarelli, A Ciucci, F Palluzzi, G Raspaglio… - Journal of Experimental …, 2022 - Springer
Background High-grade serous ovarian cancer (HGSOC) has poor survival rates due to a
combination of diagnosis at advanced stage and disease recurrence as a result of …

Cellular QoE prediction for video service based on causal structure learning

K Zhang, G Chuai, W Gao, Q Liu - IEEE Transactions on …, 2022 - ieeexplore.ieee.org
With the development of telecommunication technology and the popularity of intelligent
devices, user experience in cellular network has become the primary factor of concern. At …

Structural brain splitting is a hallmark of Granulin-related frontotemporal dementia

S Gazzina, M Grassi, E Premi, A Alberici, A Benussi… - Neurobiology of …, 2022 - Elsevier
Frontotemporal dementia associated with granulin (GRN) mutations presents asymmetric
brain atrophy. We applied a Minimum Spanning Tree plus an Efficiency Cost Optimization …

Causal Network Inference of High-Throughput Data with Structural Equation Models

B Tarantino - 2024 - iris.unipv.it
Biological and therapeutic uses for network-based approaches to human illness treatment
are numerous. A deeper understanding of the role of cellular interconnection in disease …